Cargando…

Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage

Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza, with strong antioxidant effects. Recent findings have shown that Sal B has anti-inflammatory, anti-apoptotic, anti-fibrotic effects and can promote stem cell proliferation and differentiation, and has a benefici...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Zhun, Liu, Wei, Mu, Yong-ping, Zhang, Hua, Wang, Xiao-ning, Zhao, Chang-qing, Chen, Jia-mei, Liu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741185/ https://www.ncbi.nlm.nih.gov/pubmed/33343348 http://dx.doi.org/10.3389/fphar.2020.572373

Ejemplares similares

Network pharmacology-based analysis of potential mechanisms of myocardial ischemia-reperfusion injury by total salvianolic acid injection
por: Li, Nan, et al.
Publicado: (2023)

Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice
por: Yang, Zhen, et al.
Publicado: (2021)

Salvianolic Acid B and Ginsenoside Re Synergistically Protect Against Ox-LDL-Induced Endothelial Apoptosis Through the Antioxidative and Antiinflammatory Mechanisms
por: Yang, Ke, et al.
Publicado: (2018)

Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury
por: Hou, Shuai, et al.
Publicado: (2016)

Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice
por: Li, Songtao, et al.
Publicado: (2020)

Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo
por: Wu, Yifan, et al.
Publicado: (2020)

Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress
por: Mai, Xiaoyi, et al.
Publicado: (2020)

Salvianolic acid B inhibits autophagy and activation of hepatic stellate cells induced by TGF-β1 by downregulating the MAPK pathway
por: Jiang, Na, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking-Based Mechanism Study to Reveal the Protective Effect of Salvianolic Acid C in a Rat Model of Ischemic Stroke
por: Yang, Yuting, et al.
Publicado: (2022)

Effects and Mechanism of Salvianolic Acid B on the Injury of Human Renal Tubular Epithelial Cells Induced by Iopromide
por: Dong, Shu-Jun, et al.
Publicado: (2021)

Exploration of the Mechanism of Salvianolic Acid for Injection Against Ischemic Stroke: A Research Based on Computational Prediction and Experimental Validation
por: Li, Xiaoqiang, et al.
Publicado: (2022)

Salvianolic Acids: Potential Source of Natural Drugs for the Treatment of Fibrosis Disease and Cancer
por: Ma, Lunkun, et al.
Publicado: (2019)

Salvianolic Acid B Inhibits Activation of Human Primary Hepatic Stellate Cells Through Downregulation of the Myocyte Enhancer Factor 2 Signaling Pathway
por: Zhang, Wenwei, et al.
Publicado: (2019)

Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent
por: Guo, Sha-Sha, et al.
Publicado: (2022)

Salvianolic Acid A Ameliorates Arsenic Trioxide-Induced Cardiotoxicity Through Decreasing Cardiac Mitochondrial Injury and Promotes Its Anticancer Activity
por: Zhang, Jing-yi, et al.
Publicado: (2018)

Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy
por: Lin, Jinti, et al.
Publicado: (2018)

Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis
por: Zhu, Ji, et al.
Publicado: (2022)

Network Pharmacology Analyses of the Pharmacological Targets and Therapeutic Mechanisms of Salvianolic Acid A in Myocardial Infarction
por: Huang, Qing, et al.
Publicado: (2022)

Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway
por: Zhu, Jie, et al.
Publicado: (2018)

Specific Combination of Salvianolic Acids As Core Active Ingredients of Danhong Injection for Treatment of Arterial Thrombosis and Its Derived Dry Gangrene
por: Zhao, Tiechan, et al.
Publicado: (2017)

Computational and experimental studies of salvianolic acid A targets 3C protease to inhibit enterovirus 71 infection
por: Shi, Sai, et al.
Publicado: (2023)

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro
por: Dai, Jian-Ping, et al.
Publicado: (2015)

Protective Effect of Isoorientin on Oleic Acid-Induced Oxidative Damage and Steatosis in Rat Liver Cells
por: Luo, Tongwang, et al.
Publicado: (2022)

The Effects of Salvianolate Combined With Western Medicine on Diabetic Nephropathy: A Systematic Review and Meta-Analysis
por: Shen, Yuehong, et al.
Publicado: (2020)

An Update on AMPK in Hydrogen Sulfide Pharmacology
por: Wang, Minjun, et al.
Publicado: (2017)

Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1–Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway
por: Pang, Yu, et al.
Publicado: (2020)

Salvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis Model
por: Xiong, Yongjian, et al.
Publicado: (2016)

Safety, tolerance, and pharmacokinetics of salvianolic acid B in healthy Chinese volunteers: A randomized, double-blind, placebo-controlled phase 1 clinical trial
por: Cheng, Junlin, et al.
Publicado: (2023)

Five Active Components Compatibility of Astragali Radix and Angelicae Sinensis Radix Protect Hematopoietic Function Against Cyclophosphamide-Induced Injury in Mice and t-BHP–Induced Injury in HSCs
por: Zhang, Wei, et al.
Publicado: (2019)

Salvianolate Ameliorates Osteopenia and Improves Bone Quality in Prednisone-Treated Rheumatoid Arthritis Rats by Regulating RANKL/RANK/OPG Signaling
por: Gao, Xiang, et al.
Publicado: (2021)

Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING
por: Yu, Ting-Ting, et al.
Publicado: (2022)

First-in-human study to investigate the safety and pharmacokinetics of salvianolic acid A and pharmacokinetic simulation using a physiologically based pharmacokinetic model
por: Chen, Jinliang, et al.
Publicado: (2022)

Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage
por: Li, Jing, et al.
Publicado: (2014)

Proteomics Unravels Emodin Causes Liver Oxidative Damage Elicited by Mitochondrial Dysfunction
por: Zhang, Yinhuan, et al.
Publicado: (2020)

Pharmacological Inhibition of Fatty Acid-Binding Protein 4 (FABP4) Protects Against Rhabdomyolysis-Induced Acute Kidney Injury
por: Huang, Rongshuang, et al.
Publicado: (2018)

Salvianolic acid B attenuates inflammation and prevent pathologic fibrosis by inhibiting CD36-mediated activation of the PI3K-Akt signaling pathway in frozen shoulder
por: Yan, Yan, et al.
Publicado: (2023)

An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid
por: Ma, Chongyang, et al.
Publicado: (2020)

SNS-032 attenuates liver fibrosis by anti-active hepatic stellate cells via inhibition of cyclin dependent kinase 9
por: He, Xiao-Li, et al.
Publicado: (2022)

Salvianolic Acid A Protects against Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Neutrophil NETosis
por: Liu, Qiang, et al.
Publicado: (2022)

Advances in the therapeutic application and pharmacological properties of kinsenoside against inflammation and oxidative stress-induced disorders
por: Lu, Li, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_af3lpbsiseea5hnja5mk9v4gi4