Cargando…

Bereavement and Physiological Dysregulations in African American Adults

This study uses data from National Survey of Midlife in the U.S. (MIDUS) to examine the effect of bereavement on physiological dysregulations in African American adults, with moderating effects of gender. Models were estimated using data from 210 Non-Hispanic African American respondents who partici...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jieun, Mailick, Marsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741322/
http://dx.doi.org/10.1093/geroni/igaa057.3424
_version_ 1783623726949990400
author Song, Jieun
Mailick, Marsha
author_facet Song, Jieun
Mailick, Marsha
author_sort Song, Jieun
collection PubMed
description This study uses data from National Survey of Midlife in the U.S. (MIDUS) to examine the effect of bereavement on physiological dysregulations in African American adults, with moderating effects of gender. Models were estimated using data from 210 Non-Hispanic African American respondents who participated in MIDUS 2 (M2: 2004-2005) and the biomarker data collection (2004-2009). We analyzed data from two groups, respondents who experienced the death of an individual(s) close to them, either family or friends (97 women, 40 men) and respondents who did not experience any deaths of close individuals during the same period (46 women, 27 men), controlling for age, education, marital status, prior family bereavement, number of negative life events since M2, and physical health prior to bereavement. Physiological dysregulations were assessed for 7 systems: HPA axis, glucose metabolism, lipids metabolism, sympathetic system, parasympathetic system, inflammation, and cardiovascular functioning. The results show that African American men and women who experienced bereavement were at higher risk of dysregulation of glucose metabolism (assessed by HbA1c, HOMA-IR, and fasting glucose) than the non-bereaved, even after adjusting prior diabetes diagnosis. In addition, African American women (but not men) who experienced recent bereavement were at higher risk of dysregulation of HPA axis functioning (assessed by urinary cortisol and blood DHEA-S) than their counterparts. The other physiological systems were not significantly associated with bereavement experience in African American adults. The findings suggest that bereavement has adverse impacts on health in African American adults via dysregulations in glucose metabolism and HPA axis functioning.
format Online
Article
Text
id pubmed-7741322
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-77413222020-12-21 Bereavement and Physiological Dysregulations in African American Adults Song, Jieun Mailick, Marsha Innov Aging Abstracts This study uses data from National Survey of Midlife in the U.S. (MIDUS) to examine the effect of bereavement on physiological dysregulations in African American adults, with moderating effects of gender. Models were estimated using data from 210 Non-Hispanic African American respondents who participated in MIDUS 2 (M2: 2004-2005) and the biomarker data collection (2004-2009). We analyzed data from two groups, respondents who experienced the death of an individual(s) close to them, either family or friends (97 women, 40 men) and respondents who did not experience any deaths of close individuals during the same period (46 women, 27 men), controlling for age, education, marital status, prior family bereavement, number of negative life events since M2, and physical health prior to bereavement. Physiological dysregulations were assessed for 7 systems: HPA axis, glucose metabolism, lipids metabolism, sympathetic system, parasympathetic system, inflammation, and cardiovascular functioning. The results show that African American men and women who experienced bereavement were at higher risk of dysregulation of glucose metabolism (assessed by HbA1c, HOMA-IR, and fasting glucose) than the non-bereaved, even after adjusting prior diabetes diagnosis. In addition, African American women (but not men) who experienced recent bereavement were at higher risk of dysregulation of HPA axis functioning (assessed by urinary cortisol and blood DHEA-S) than their counterparts. The other physiological systems were not significantly associated with bereavement experience in African American adults. The findings suggest that bereavement has adverse impacts on health in African American adults via dysregulations in glucose metabolism and HPA axis functioning. Oxford University Press 2020-12-16 /pmc/articles/PMC7741322/ http://dx.doi.org/10.1093/geroni/igaa057.3424 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Song, Jieun
Mailick, Marsha
Bereavement and Physiological Dysregulations in African American Adults
title Bereavement and Physiological Dysregulations in African American Adults
title_full Bereavement and Physiological Dysregulations in African American Adults
title_fullStr Bereavement and Physiological Dysregulations in African American Adults
title_full_unstemmed Bereavement and Physiological Dysregulations in African American Adults
title_short Bereavement and Physiological Dysregulations in African American Adults
title_sort bereavement and physiological dysregulations in african american adults
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741322/
http://dx.doi.org/10.1093/geroni/igaa057.3424
work_keys_str_mv AT songjieun bereavementandphysiologicaldysregulationsinafricanamericanadults
AT mailickmarsha bereavementandphysiologicaldysregulationsinafricanamericanadults