A DNA Damage Response-Independent Mechanism for Telomere Shortening-Elicited Age-Related Pathologies

Telomere attrition is associated with telomeropathies and age-related pathologies. In telomeropathies, telomere uncapping induces a DNA damage response (DDR) that drives apoptosis or senescence. However, a defined mechanism by which telomere attrition contributes to other age-related pathologies has...

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Detalles Bibliográficos
Autores principales: Stock, Amanda, Wang, Kun, Sun, Chongkui, Liu, Chengyu, Gong, Yi, Liu, Yie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741410/
http://dx.doi.org/10.1093/geroni/igaa057.3268

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