Cargando…

Determining the Role of ApoE4 in Age-Related Cerebrovascular Decline

Cerebrovascular decline occurs during aging and may be critical during prodromal phases of Alzheimer’s disease (AD). The E4 allele of apolipoprotein E (APOE4) is the greatest genetic risk factor for AD and decreased longevity and studies suggest APOE4 increases risk for age-dependent cerebrovascular...

Descripción completa

Detalles Bibliográficos
Autores principales:	Foley, Kate, Borchian, Peter, Garceau, Dylan, Kotredes, Kevin, Territo, Paul, Sasner, Michael, Howell, Gareth, Diemler, Cory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741542/ http://dx.doi.org/10.1093/geroni/igaa057.390

Ejemplares similares

APOE ε4 and exercise interact in a sex‐specific manner to modulate dementia risk factors
por: Foley, Kate E., et al.
Publicado: (2022)

The APOE(ε3/ε4) Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice
por: Foley, Kate E., et al.
Publicado: (2022)

Aging Related Transcriptomic Changes in the Mouse Models of Alzheimer’s Disease
por: Uyar, Asli, et al.
Publicado: (2020)

Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H
por: Kotredes, Kevin P., et al.
Publicado: (2021)

Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2(*)R47H
por: Kotredes, Kevin P., et al.
Publicado: (2022)

Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer’s disease
por: Pandey, Ravi S., et al.
Publicado: (2023)

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
por: Preuss, Christoph, et al.
Publicado: (2020)

Transcriptional profiling predicts running promotes cerebrovascular remodeling in young but not midlife mice
por: Foley, Kate E., et al.
Publicado: (2019)

Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study
por: Oblak, Adrian L., et al.
Publicado: (2021)

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction
por: Brandon, Jason A., et al.
Publicado: (2018)

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma
por: Buchanan, Rebecca A., et al.
Publicado: (2019)

The Impact of ApoE e4 Allele in the Effects of Physical Activity Interventions on Major Mobility Disability Incidence
por: Cenko, Erta, et al.
Publicado: (2020)

PT593. CSF Beta-Amyloid and APOE E4 Related Decline in Episodic Memory over 12 months measured using the CANTAB in individuals with amnestic MCI: Results from the European-ADNI study
por: Nathan, Pradeep J., et al.
Publicado: (2016)

Interactions Between Plasma Amyloid and Aging Markers to Determine Clinically Meaningful Cognitive Decline
por: Lu, Wan-Hsuan, et al.
Publicado: (2021)

Apolipoprotein-E (Apoe) ε4 and cognitive decline over the adult life course
por: Rawle, Mark James, et al.
Publicado: (2018)

Effect of APOE and CD33 on Cognitive Decline
por: Hayden, Kathleen M., et al.
Publicado: (2015)

Early Differences in Cognition Associated With Familial Longevity and ApoE Genotype Using Digital Technology
por: Andersen, Stacy, et al.
Publicado: (2020)

IMPACT OF COMBINATIONS OF THE APOE Ɛ4 ALLELE AND TOMM40-APOC1 VARIANTS ON SURVIVAL TO OLDER AGES AND ALZHEIMER’S RISK
por: Kulminski, Alexander, et al.
Publicado: (2022)

Functional MRI and ApoE4 genotype for predicting cognitive decline in amyloid-positive individuals
por: Zhu, Jun-Ding, et al.
Publicado: (2022)

APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction
por: Soto, Ileana, et al.
Publicado: (2015)

Gender-Specific Determinants of Instrumental Activities and Associations With Cognitive Decline in TILDA
por: McGarrigle, Christine, et al.
Publicado: (2020)

Effect of plasma lipids and APOE genotype on cognitive decline
por: Yasuno, Fumihiko, et al.
Publicado: (2013)

Correction: Effect of APOE and CD33 on Cognitive Decline
por: Hayden, Kathleen M., et al.
Publicado: (2015)

APOE-ɛ4 effects on longitudinal decline in olfactory and non-olfactory cognitive abilities in middle-aged and old adults
por: Josefsson, Maria, et al.
Publicado: (2017)

The Impact of ApoE and FOXO3 Genotype on the Risk of Intracerebral Hemorrhage Among American Men of Japanese Ancestry
por: Nakagawa, Kazuma, et al.
Publicado: (2021)

Diminished circulating retinol and elevated α-TOH/retinol ratio predict an increased risk of cognitive decline in aging Chinese adults, especially in subjects with ApoE2 or ApoE4 genotype
por: Huang, Xiaochen, et al.
Publicado: (2018)

Citicoline May Prevent Cognitive Decline in Patients with Cerebrovascular Disease
por: Almeria, Marta, et al.
Publicado: (2023)

Race, APOE genotypes, and cognitive decline among middle-aged urban adults
por: Beydoun, May A., et al.
Publicado: (2021)

CSF Potential Biomarkers Aβ42 and Tau: associations of Apo E Genotype
por: Kandimalla, Ramesh, et al.
Publicado: (2010)

ApoE and apoE receptors in brain lipid metabolism and AD
por: Bu, Guojun
Publicado: (2012)

Spatial patterns of tau deposition are associated with amyloid, ApoE, sex, and cognitive decline in older adults
por: Pereira, Joana B., et al.
Publicado: (2020)

Plcg2(M28L) Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer’s Disease-Relevant Phenotypes in Mice
por: Oblak, Adrian L., et al.
Publicado: (2022)

THE COMPARISON OF DUAL TASK TIME AMONG APOE CARRIERS AGAINST NON-APOE CARRIERS IN AGING ADULTS
por: Diehl, Cody, et al.
Publicado: (2022)

Protection against APOE4-associated aging phenotypes with a longevity-promoting intervention
por: McGill, Cassandra, et al.
Publicado: (2021)

The role of APOE in cognitive trajectories and motor decline in Parkinson’s disease
por: Jo, Sungyang, et al.
Publicado: (2021)

Longitudinal progression of choroid plexus enlargement is associated with female sex, cognitive decline and ApoE E4 homozygote status
por: Novakova Martinkova, Julie, et al.
Publicado: (2023)

Electrocardiographic abnormalities in patients with cerebrovascular disease
por: Passavanti, MB, et al.
Publicado: (1998)

Post Cerebrovascular Stroke Catatonic Psychosis: A Case Report
por: Hasan, H., et al.
Publicado: (2023)

Epidermal growth factor prevents APOE4-induced cognitive and cerebrovascular deficits in female mice
por: Thomas, Riya, et al.
Publicado: (2017)

Cerebrovascular Changes and Neurodegeneration Related to Hyperlipidemia: Characteristics of the Human ApoB-100 Transgenic Mice
por: Tóth, Melinda E., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e1aipb8okmvebrm0q4j40rgva5