Cargando…
Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis
Existing literature indicates a relatively consistent relationship between neuroticism and cognitive functioning (CF). Interindividually, high levels of neuroticism may predispose individuals to cognitive aging and dementia-related neuropathology. Intraindividually, increases in neuroticism may be i...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741976/ http://dx.doi.org/10.1093/geroni/igaa057.1248 |
_version_ | 1783623879157088256 |
---|---|
author | Yoneda, Tomiko Rush, Jonathan Terrera, Graciela Muniz Kok, Almar Johansson, Boo Hofer, Scott Mroczek, Daniel Piccinin, Andrea |
author_facet | Yoneda, Tomiko Rush, Jonathan Terrera, Graciela Muniz Kok, Almar Johansson, Boo Hofer, Scott Mroczek, Daniel Piccinin, Andrea |
author_sort | Yoneda, Tomiko |
collection | PubMed |
description | Existing literature indicates a relatively consistent relationship between neuroticism and cognitive functioning (CF). Interindividually, high levels of neuroticism may predispose individuals to cognitive aging and dementia-related neuropathology. Intraindividually, increases in neuroticism may be intrinsic to the aging process or to dementia pathology. These hypotheses are not mutually exclusive, though the relationships are rarely examined using the same individuals, which may contribute to publication bias and confusion regarding the hypotheses as mutually exclusive. Data were drawn from the Origins of Variance in the Oldest-Old (Sweden, Mage=83.6, 67% female), Swedish Adoption/Twin Study of Aging (Sweden, Mage=60.4, 59% female), and Longitudinal Aging Study Amsterdam (Netherlands; Mage=68.1, 52% female). Controlling for age, sex, education, and depressive symptoms, parallel process latent growth models were fit independently in each sample (NT=3293) to simultaneously estimate growth parameters of neuroticism with three measures of CF (processing speed, learning/memory, and reasoning). Multilevel meta-analysis estimated the pooled covariation between neuroticism and CF at baseline and overtime, revealing a significantly negative intercept-intercept relationship across datasets (covariance= -0.46, 95% CIs [-0.90,-0.02], z=-2.02, p=0.04, τ2=0.06). The slope-slope covariances were consistently negative, but the meta-analytic pooled estimate was not significant despite some significant individual estimates across studies. Overall, results provide some evidence for intraindividual and interindividual relationships between neuroticism and CF, such that higher neuroticism is associated with lower CF, and neuroticism tends to increase as CF decreases. Identification of the early indicators and risk factors for cognitive decline may facilitate development of screening assessments and aid in treatment strategies for dementia care services. |
format | Online Article Text |
id | pubmed-7741976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-77419762020-12-21 Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis Yoneda, Tomiko Rush, Jonathan Terrera, Graciela Muniz Kok, Almar Johansson, Boo Hofer, Scott Mroczek, Daniel Piccinin, Andrea Innov Aging Abstracts Existing literature indicates a relatively consistent relationship between neuroticism and cognitive functioning (CF). Interindividually, high levels of neuroticism may predispose individuals to cognitive aging and dementia-related neuropathology. Intraindividually, increases in neuroticism may be intrinsic to the aging process or to dementia pathology. These hypotheses are not mutually exclusive, though the relationships are rarely examined using the same individuals, which may contribute to publication bias and confusion regarding the hypotheses as mutually exclusive. Data were drawn from the Origins of Variance in the Oldest-Old (Sweden, Mage=83.6, 67% female), Swedish Adoption/Twin Study of Aging (Sweden, Mage=60.4, 59% female), and Longitudinal Aging Study Amsterdam (Netherlands; Mage=68.1, 52% female). Controlling for age, sex, education, and depressive symptoms, parallel process latent growth models were fit independently in each sample (NT=3293) to simultaneously estimate growth parameters of neuroticism with three measures of CF (processing speed, learning/memory, and reasoning). Multilevel meta-analysis estimated the pooled covariation between neuroticism and CF at baseline and overtime, revealing a significantly negative intercept-intercept relationship across datasets (covariance= -0.46, 95% CIs [-0.90,-0.02], z=-2.02, p=0.04, τ2=0.06). The slope-slope covariances were consistently negative, but the meta-analytic pooled estimate was not significant despite some significant individual estimates across studies. Overall, results provide some evidence for intraindividual and interindividual relationships between neuroticism and CF, such that higher neuroticism is associated with lower CF, and neuroticism tends to increase as CF decreases. Identification of the early indicators and risk factors for cognitive decline may facilitate development of screening assessments and aid in treatment strategies for dementia care services. Oxford University Press 2020-12-16 /pmc/articles/PMC7741976/ http://dx.doi.org/10.1093/geroni/igaa057.1248 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstracts Yoneda, Tomiko Rush, Jonathan Terrera, Graciela Muniz Kok, Almar Johansson, Boo Hofer, Scott Mroczek, Daniel Piccinin, Andrea Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis |
title | Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis |
title_full | Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis |
title_fullStr | Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis |
title_full_unstemmed | Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis |
title_short | Inter-Individual and Intra-Individual Relationships Between Neuroticism and Cognition: A Coordinated Analysis |
title_sort | inter-individual and intra-individual relationships between neuroticism and cognition: a coordinated analysis |
topic | Abstracts |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7741976/ http://dx.doi.org/10.1093/geroni/igaa057.1248 |
work_keys_str_mv | AT yonedatomiko interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT rushjonathan interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT terreragracielamuniz interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT kokalmar interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT johanssonboo interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT hoferscott interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT mroczekdaniel interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis AT piccininandrea interindividualandintraindividualrelationshipsbetweenneuroticismandcognitionacoordinatedanalysis |