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Effects of Omecamtiv Mecarbil on Symptoms and Health-Related Quality of Life in Patients With Chronic Heart Failure: Results From the COSMIC-HF Study

Chronic heart failure with reduced ejection fraction impairs health-related quality of life (HRQL). Omecamtiv mecarbil (OM)—a novel activator of cardiac myosin—improves left ventricular systolic function and remodeling and reduces natriuretic peptides. We sought to evaluate the effect of OM on sympt...

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Detalles Bibliográficos
Autores principales: Felker, G. Michael, Solomon, Scott D., McMurray, John J.V., Cleland, John G.F., Abbasi, Siddique A., Malik, Fady I., Zhang, Hanze, Globe, Gary, Teerlink, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742205/
https://www.ncbi.nlm.nih.gov/pubmed/33176437
http://dx.doi.org/10.1161/CIRCHEARTFAILURE.120.007814