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Neurons Putting Out the Trash: A Novel Facet of Proteostasis and Mitochondrial Quality Control

Toxicity of misfolded proteins and mitochondrial dysfunction are pivotal factors that promote age-associated functional neuronal decline and neurodegenerative disease across species. Although these neurotoxic challenges have long been considered to be cell-intrinsic, considerable evidence now suppor...

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Detalles Bibliográficos
Autor principal: Driscoll, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742225/
http://dx.doi.org/10.1093/geroni/igaa057.2633