Age-Related Increased Onset and Progression of Prostate Cancer Is Revealed in Novel Pten-Null Mouse Models

Prostate cancer (PCa) is associated with advanced age. To better understand how age impacts PCa, it is critical to use PCa animal models generated at different ages (aged vs. non-aged). The PB-Cre4 driven phosphatase and tensin homolog (Pten) conditional knockout mouse model, which closely imitates...

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Detalles Bibliográficos
Autores principales: Zhang, Qiuyang, Liu, Sen, Zhang, Bing, Abdel-Mageed, Asim, Steele, Chad, Wang, Alun, Jazwinski, S, Myers, Leann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742314/
http://dx.doi.org/10.1093/geroni/igaa057.425

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