Cargando…

REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function

Since 2003, REGARDS participants have taken part in telephone-based cognitive assessments. Global cognitive status is assessed annually with the Six-item Screener. Between 2006 and 2009, measures of learning and memory (CERAD Word List) and language/executive function (Animal and Letter Fluency) wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Manly, Jennifer, Unverzagt, Frederick, McClure, Leslie, Judd, Suzanne, Rhodes, J David, Howard, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742389/
http://dx.doi.org/10.1093/geroni/igaa057.3152
_version_ 1783623976899051520
author Manly, Jennifer
Unverzagt, Frederick
McClure, Leslie
Judd, Suzanne
Rhodes, J David
Howard, George
author_facet Manly, Jennifer
Unverzagt, Frederick
McClure, Leslie
Judd, Suzanne
Rhodes, J David
Howard, George
author_sort Manly, Jennifer
collection PubMed
description Since 2003, REGARDS participants have taken part in telephone-based cognitive assessments. Global cognitive status is assessed annually with the Six-item Screener. Between 2006 and 2009, measures of learning and memory (CERAD Word List) and language/executive function (Animal and Letter Fluency) were implemented, and are administered biennially. A Brain Health Substudy, conducting in-home clinical examinations of neuropsychological, neurological, and functional status among 1000 participants, is underway to validate telephone assessments and estimate prevalence of VCID in REGARDS. Approaches to defining incident cognitive impairment and cognitive change, including definitions employed for case/cohort studies using stored blood samples, will be described. We will discuss psychometric and methodological considerations for characterization of risks for cognitive impairment across race and region, as well as longitudinal trajectories of cognitive function.
format Online
Article
Text
id pubmed-7742389
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-77423892020-12-21 REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function Manly, Jennifer Unverzagt, Frederick McClure, Leslie Judd, Suzanne Rhodes, J David Howard, George Innov Aging Abstracts Since 2003, REGARDS participants have taken part in telephone-based cognitive assessments. Global cognitive status is assessed annually with the Six-item Screener. Between 2006 and 2009, measures of learning and memory (CERAD Word List) and language/executive function (Animal and Letter Fluency) were implemented, and are administered biennially. A Brain Health Substudy, conducting in-home clinical examinations of neuropsychological, neurological, and functional status among 1000 participants, is underway to validate telephone assessments and estimate prevalence of VCID in REGARDS. Approaches to defining incident cognitive impairment and cognitive change, including definitions employed for case/cohort studies using stored blood samples, will be described. We will discuss psychometric and methodological considerations for characterization of risks for cognitive impairment across race and region, as well as longitudinal trajectories of cognitive function. Oxford University Press 2020-12-16 /pmc/articles/PMC7742389/ http://dx.doi.org/10.1093/geroni/igaa057.3152 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Manly, Jennifer
Unverzagt, Frederick
McClure, Leslie
Judd, Suzanne
Rhodes, J David
Howard, George
REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function
title REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function
title_full REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function
title_fullStr REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function
title_full_unstemmed REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function
title_short REGARDS Cognitive Assessment and Approaches to Defining Cognitive Impairment and Change in Cognitive Function
title_sort regards cognitive assessment and approaches to defining cognitive impairment and change in cognitive function
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742389/
http://dx.doi.org/10.1093/geroni/igaa057.3152
work_keys_str_mv AT manlyjennifer regardscognitiveassessmentandapproachestodefiningcognitiveimpairmentandchangeincognitivefunction
AT unverzagtfrederick regardscognitiveassessmentandapproachestodefiningcognitiveimpairmentandchangeincognitivefunction
AT mcclureleslie regardscognitiveassessmentandapproachestodefiningcognitiveimpairmentandchangeincognitivefunction
AT juddsuzanne regardscognitiveassessmentandapproachestodefiningcognitiveimpairmentandchangeincognitivefunction
AT rhodesjdavid regardscognitiveassessmentandapproachestodefiningcognitiveimpairmentandchangeincognitivefunction
AT howardgeorge regardscognitiveassessmentandapproachestodefiningcognitiveimpairmentandchangeincognitivefunction