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Mechanisms of Lifespan Extension by Sirt6 in Drosophila melanogaster

Sirt6 is a multifunctional enzyme that regulates numerous cellular processes connected to longevity. Overexpressing Sirt6 extends lifespan in mice, but the underlying cellular mechanisms are unclear. Here, we used the powerful genetic tools and short lifespan of Drosophila melanogaster to better und...

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Detalles Bibliográficos
Autores principales: Taylor, Jackson, Wood, Jason, Finn, Matthew, Liu, Julianna, Mizerak, Evan, Gordon, Sarah, Hutfilz, Corinne, Helfand, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742554/
http://dx.doi.org/10.1093/geroni/igaa057.2617

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