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Mechanisms of Lifespan Extension by Sirt6 in Drosophila melanogaster
Sirt6 is a multifunctional enzyme that regulates numerous cellular processes connected to longevity. Overexpressing Sirt6 extends lifespan in mice, but the underlying cellular mechanisms are unclear. Here, we used the powerful genetic tools and short lifespan of Drosophila melanogaster to better und...
Autores principales: | Taylor, Jackson, Wood, Jason, Finn, Matthew, Liu, Julianna, Mizerak, Evan, Gordon, Sarah, Hutfilz, Corinne, Helfand, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742554/ http://dx.doi.org/10.1093/geroni/igaa057.2617 |
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