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Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study

The concept of resilience has gained increasing attention in aging research; however, current literature lacks consensus on how to measure resilience. We constructed a novel resilience measure based on the degree of mismatch between persons’ frailty level and disease burden and examined its predicti...

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Autores principales: Wu, Chenkai, Li, Ya-Xi, Odden, Michelle, Marron, Megan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742644/
http://dx.doi.org/10.1093/geroni/igaa057.1578
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author Wu, Chenkai
Li, Ya-Xi
Odden, Michelle
Marron, Megan
author_facet Wu, Chenkai
Li, Ya-Xi
Odden, Michelle
Marron, Megan
author_sort Wu, Chenkai
collection PubMed
description The concept of resilience has gained increasing attention in aging research; however, current literature lacks consensus on how to measure resilience. We constructed a novel resilience measure based on the degree of mismatch between persons’ frailty level and disease burden and examined its predictive validity. We also sought to explore the physiological correlates of resilience. Participants were 2,457 older adults from the Health, Aging, and Body Composition Study. We constructed the resilience measure as the residual taken from the linear model regressing frailty on age, sex, race/ethnicity, 14 diseases, self-reported health, and number of medications. Participants were classified into three groups—adapters, expected agers, and premature frailers—based on residuals (less than, within, or above one standard deviation of the mean). Validation outcomes included years of able life (YAL), years of healthy life (YHL), years of healthy and able life (YHAL), disability, hospitalization, and survival. The average YHAL was 5.1, 7.7, and 9.1 years among premature frailers, expected agers, and adapters, respectively. Compared with premature frailers and expected agers, adapters had significantly lower rates of disability, hospitalization, and mortality and higher proportion surviving to 90 years. The likelihood of surviving to 90 years was 20.4%, 30.6%, and 39.7% among premature frailers, expected agers, and adapters. We developed and validated a novel approach for quantifying and classifying physical resilience in a cohort of well-functioning white and black older adults. Persons with high physical resilience level had longer healthy life span and lower rates of adverse outcomes.
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spelling pubmed-77426442020-12-21 Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study Wu, Chenkai Li, Ya-Xi Odden, Michelle Marron, Megan Innov Aging Abstracts The concept of resilience has gained increasing attention in aging research; however, current literature lacks consensus on how to measure resilience. We constructed a novel resilience measure based on the degree of mismatch between persons’ frailty level and disease burden and examined its predictive validity. We also sought to explore the physiological correlates of resilience. Participants were 2,457 older adults from the Health, Aging, and Body Composition Study. We constructed the resilience measure as the residual taken from the linear model regressing frailty on age, sex, race/ethnicity, 14 diseases, self-reported health, and number of medications. Participants were classified into three groups—adapters, expected agers, and premature frailers—based on residuals (less than, within, or above one standard deviation of the mean). Validation outcomes included years of able life (YAL), years of healthy life (YHL), years of healthy and able life (YHAL), disability, hospitalization, and survival. The average YHAL was 5.1, 7.7, and 9.1 years among premature frailers, expected agers, and adapters, respectively. Compared with premature frailers and expected agers, adapters had significantly lower rates of disability, hospitalization, and mortality and higher proportion surviving to 90 years. The likelihood of surviving to 90 years was 20.4%, 30.6%, and 39.7% among premature frailers, expected agers, and adapters. We developed and validated a novel approach for quantifying and classifying physical resilience in a cohort of well-functioning white and black older adults. Persons with high physical resilience level had longer healthy life span and lower rates of adverse outcomes. Oxford University Press 2020-12-16 /pmc/articles/PMC7742644/ http://dx.doi.org/10.1093/geroni/igaa057.1578 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Wu, Chenkai
Li, Ya-Xi
Odden, Michelle
Marron, Megan
Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study
title Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study
title_full Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study
title_fullStr Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study
title_full_unstemmed Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study
title_short Creating a Novel Physical Resilience Measure among Older Adults: The Health, Aging, and Body Composition Study
title_sort creating a novel physical resilience measure among older adults: the health, aging, and body composition study
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742644/
http://dx.doi.org/10.1093/geroni/igaa057.1578
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