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Age-Dependent Changes in Nuclear Mechanotransduction as a Driver of Sarcopenia

Informed by evidence that dysregulated nuclear dynamics and nuclear transport may contribute to atrophy in diseased skeletal muscle, the purpose of this study was to assess nuclear deformability, permeability, transport, and mechano-signaling outputs (YAP/TAZ, a marker of mechano-responsiveness, and...

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Detalles Bibliográficos
Autores principales:	Iyer, Shama, Ward, Christopher, Stains, Joseph, Ryan, Alice, Folker, Eric, Lovering, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7742940/ http://dx.doi.org/10.1093/geroni/igaa057.424

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