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Senescence and Senolytics: State of the Art on Cellular Senescence, Senolytics, and Healthspan
Cellular senescence is a cell fate decision that is made by many mammalian cell types in response to damage, stress or certain physiological signals. Senescent cells arrest proliferation, essentially permanently, and develop a complex multi-component senescence-associated secretory phenotype (SASP)....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743053/ http://dx.doi.org/10.1093/geroni/igaa057.2654 |