Natural SARS-CoV-2 infections, including virus isolation, among serially tested cats and dogs in households with confirmed human COVID-19 cases in Texas, USA

The natural infections and epidemiological roles of household pets in SARS-CoV-2 transmission are not understood. We conducted a longitudinal study of dogs and cats living with at least one SARS-CoV-2 infected human in Texas and found 47.1% of 17 cats and 15.3% of 59 dogs from 25.6% of 39 households...

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Detalles Bibliográficos
Autores principales: Hamer, Sarah A., Pauvolid-Corrêa, Alex, Zecca, Italo B., Davila, Edward, Auckland, Lisa D., Roundy, Christopher M., Tang, Wendy, Torchetti, Mia, Killian, Mary Lea, Jenkins-Moore, Melinda, Mozingo, Katie, Akpalu, Yao, Ghai, Ria R., Spengler, Jessica R., Behravesh, Casey Barton, Fischer, Rebecca S. B., Hamer, Gabriel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743065/
https://www.ncbi.nlm.nih.gov/pubmed/33330861
http://dx.doi.org/10.1101/2020.12.08.416339
Descripción
Sumario:The natural infections and epidemiological roles of household pets in SARS-CoV-2 transmission are not understood. We conducted a longitudinal study of dogs and cats living with at least one SARS-CoV-2 infected human in Texas and found 47.1% of 17 cats and 15.3% of 59 dogs from 25.6% of 39 households were positive for SARS-CoV-2 via RT-PCR and genome sequencing or neutralizing antibodies. Virus was isolated from one cat. The majority (82.4%) of infected pets were asymptomatic. Re-sampling of one infected cat showed persistence of viral RNA at least 32 d-post human diagnosis (25 d-post initial test). Across 15 antibody-positive animals, titers increased (33.3%), decreased (33.3%) or were stable (33.3%) over time. A One Health approach is informative for prevention and control of SARS-CoV-2 transmission.

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