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Bile Acids in Dementia: Brain Amyloid, White Matter Lesions, and Atrophy

While Alzheimer’s disease (AD) and vascular dementia (VaD) may be accelerated by hypercholesterolemia, the mechanisms underlying this association is unclear. Using a novel, 3-step study design we examined the role of cholesterol catabolism in dementia by testing whether 1) the synthesis of the prima...

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Detalles Bibliográficos
Autores principales: Varma, Vijay, Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Thambisetty, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743431/
http://dx.doi.org/10.1093/geroni/igaa057.2772

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