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Aging, Senescent Cells, and Senolytic Drugs: The Path to Translation
Senescent cells (SC) accumulate with aging and at causal sites of multiple chronic disorders and diseases, including those accounting for the bulk of morbidity, mortality, and health expenditures. SC do not replicate. Some SC release factors that cause tissue dysfunction, the senescence-associated s...
Autor principal: | Kirkland, James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7743618/ http://dx.doi.org/10.1093/geroni/igaa057.3198 |
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