Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients

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Recent studies have demonstrated immunologic dysfunction in severely ill coronavirus disease 2019 (COVID-19) patients. We use single-cell RNA sequencing (scRNA-seq) to analyze the transcriptome of peripheral blood mononuclear cells (PBMCs) from healthy (n = 3) and COVID-19 patients with moderate dis...

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Detalles Bibliográficos
Autores principales: Yao, Changfu, Bora, Stephanie A., Parimon, Tanyalak, Zaman, Tanzira, Friedman, Oren A., Palatinus, Joseph A., Surapaneni, Nirmala S., Matusov, Yuri P., Cerro Chiang, Giuliana, Kassar, Alexander G., Patel, Nayan, Green, Chelsi E.R., Aziz, Adam W., Suri, Harshpreet, Suda, Jo, Lopez, Andres A., Martins, Gislâine A., Stripp, Barry R., Gharib, Sina A., Goodridge, Helen S., Chen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744012/
https://www.ncbi.nlm.nih.gov/pubmed/33357411
http://dx.doi.org/10.1016/j.celrep.2020.108590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744012/
https://www.ncbi.nlm.nih.gov/pubmed/33357411
http://dx.doi.org/10.1016/j.celrep.2020.108590

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