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Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients
Recent studies have demonstrated immunologic dysfunction in severely ill coronavirus disease 2019 (COVID-19) patients. We use single-cell RNA sequencing (scRNA-seq) to analyze the transcriptome of peripheral blood mononuclear cells (PBMCs) from healthy (n = 3) and COVID-19 patients with moderate dis...
Autores principales: | Yao, Changfu, Bora, Stephanie A., Parimon, Tanyalak, Zaman, Tanzira, Friedman, Oren A., Palatinus, Joseph A., Surapaneni, Nirmala S., Matusov, Yuri P., Cerro Chiang, Giuliana, Kassar, Alexander G., Patel, Nayan, Green, Chelsi E.R., Aziz, Adam W., Suri, Harshpreet, Suda, Jo, Lopez, Andres A., Martins, Gislâine A., Stripp, Barry R., Gharib, Sina A., Goodridge, Helen S., Chen, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744012/ https://www.ncbi.nlm.nih.gov/pubmed/33357411 http://dx.doi.org/10.1016/j.celrep.2020.108590 |
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