Ambiguity Coding Allows Accurate Inference of Evolutionary Parameters from Alignments in an Aggregated State-Space

How can we best learn the history of a protein’s evolution? Ideally, a model of sequence evolution should capture both the process that generates genetic variation and the functional constraints determining which changes are fixed. However, in practical terms the most suitable approach may simply be...

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Detalles Bibliográficos
Autores principales: Weber, Claudia C, Perron, Umberto, Casey, Dearbhaile, Yang, Ziheng, Goldman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744038/
https://www.ncbi.nlm.nih.gov/pubmed/32353118
http://dx.doi.org/10.1093/sysbio/syaa036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744038/
https://www.ncbi.nlm.nih.gov/pubmed/32353118
http://dx.doi.org/10.1093/sysbio/syaa036

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