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Mapping cisplatin-induced viscosity alterations in cancer cells using molecular rotor and fluorescence lifetime imaging microscopy
Significance: Despite the importance of the cell membrane in regulation of drug activity, the influence of drug treatments on its physical properties is still poorly understood. The combination of fluorescence lifetime imaging microscopy (FLIM) with specific viscosity-sensitive fluorescent molecular...
Autores principales: | Shimolina, Liubov E., Gulin, Alexander A., Paez-Perez, Miguel, López-Duarte, Ismael, Druzhkova, Irina N., Lukina, Maria M., Gubina, Margarita V., Brooks, Nicolas J., Zagaynova, Elena V., Kuimova, Marina K., Shirmanova, Marina V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Photo-Optical Instrumentation Engineers
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744042/ https://www.ncbi.nlm.nih.gov/pubmed/33331150 http://dx.doi.org/10.1117/1.JBO.25.12.126004 |
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