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Correlation of Tumor Hypoxia Metrics Derived from (18)F-Fluoromisonidazole Positron Emission Tomography and Pimonidazole Fluorescence Images of Optically Cleared Brain Tissue
(18)F-fluoromisonidazole (FMISO) positron emission tomography (PET) is a widely used noninvasive imaging modality for assessing hypoxia. We describe the first spatial comparison of FMISO PET with an ex vivo reference standard for hypoxia across whole tumor volumes. Eighteen rats were orthotopically...
Autores principales: | Scarpelli, Matthew L., Healey, Debbie R., Fuentes, Alberto, Kodibagkar, Vikram D., Quarles, C. Chad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Grapho Publications, LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744194/ https://www.ncbi.nlm.nih.gov/pubmed/33364428 http://dx.doi.org/10.18383/j.tom.2020.00046 |
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