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Correlation of Tumor Hypoxia Metrics Derived from (18)F-Fluoromisonidazole Positron Emission Tomography and Pimonidazole Fluorescence Images of Optically Cleared Brain Tissue

(18)F-fluoromisonidazole (FMISO) positron emission tomography (PET) is a widely used noninvasive imaging modality for assessing hypoxia. We describe the first spatial comparison of FMISO PET with an ex vivo reference standard for hypoxia across whole tumor volumes. Eighteen rats were orthotopically...

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Detalles Bibliográficos
Autores principales: Scarpelli, Matthew L., Healey, Debbie R., Fuentes, Alberto, Kodibagkar, Vikram D., Quarles, C. Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Grapho Publications, LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744194/
https://www.ncbi.nlm.nih.gov/pubmed/33364428
http://dx.doi.org/10.18383/j.tom.2020.00046

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