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Subtle Influence of ACE2 Glycan Processing on SARS-CoV-2 Recognition
The severity of SARS-CoV-2 infection is highly variable and yet the molecular basis for this effect remains elusive. One potential contribution are differences in the glycosylation of target human cells, particularly as SARS-CoV-2 has the capacity to bind sialic acid which is a common, and highly va...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744274/ https://www.ncbi.nlm.nih.gov/pubmed/33340519 http://dx.doi.org/10.1016/j.jmb.2020.166762 |