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Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine

Solitary fibrous tumors are rare neoplasms that originate from mesenchymal tissues and have been found to occur in any site, including the spine and liver. Although most of solitary fibrous tumors have benign features, only 10–20% are malignant and prone to metastasis. No previous reports have descr...

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Autores principales: Mao, Min, Zhou, Lei, Huang, Chaojun, Yan, Xudong, Hu, Shuo, Yin, Huabin, Zhao, Qinghua, Song, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744481/
https://www.ncbi.nlm.nih.gov/pubmed/33344498
http://dx.doi.org/10.3389/fsurg.2020.570582
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author Mao, Min
Zhou, Lei
Huang, Chaojun
Yan, Xudong
Hu, Shuo
Yin, Huabin
Zhao, Qinghua
Song, Dianwen
author_facet Mao, Min
Zhou, Lei
Huang, Chaojun
Yan, Xudong
Hu, Shuo
Yin, Huabin
Zhao, Qinghua
Song, Dianwen
author_sort Mao, Min
collection PubMed
description Solitary fibrous tumors are rare neoplasms that originate from mesenchymal tissues and have been found to occur in any site, including the spine and liver. Although most of solitary fibrous tumors have benign features, only 10–20% are malignant and prone to metastasis. No previous reports have described the malignant and metastatic Solitary fibrous tumor arising in both of the liver and thoracic vertebrae. In this article, we present the case of a 60-year-old woman who underwent gross total resection of a meningeal tumor in 2007. She presented 10 years later with a thoracic vertebral mass that caused relentless pain and a lesion in the right lobe of liver. She underwent marginal excision of the T3 tumor with T2-4 pedicular screw fixation in March 2017, then right hemi-hepatectomy was performed to remove the liver lesion in June 2017. Both of the lesions were confirmed to be a metastatic and malignant tumor after surgery. The literature lacks randomized controlled trials and large studies that define the natural history of malignant solitary fibrous tumors and recommendations of precise management plan for the disease. However, the best choice for treatment is gross total resection, which probably provide the optimal treatment to achieve long-term disease-free survival.
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spelling pubmed-77444812020-12-18 Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine Mao, Min Zhou, Lei Huang, Chaojun Yan, Xudong Hu, Shuo Yin, Huabin Zhao, Qinghua Song, Dianwen Front Surg Surgery Solitary fibrous tumors are rare neoplasms that originate from mesenchymal tissues and have been found to occur in any site, including the spine and liver. Although most of solitary fibrous tumors have benign features, only 10–20% are malignant and prone to metastasis. No previous reports have described the malignant and metastatic Solitary fibrous tumor arising in both of the liver and thoracic vertebrae. In this article, we present the case of a 60-year-old woman who underwent gross total resection of a meningeal tumor in 2007. She presented 10 years later with a thoracic vertebral mass that caused relentless pain and a lesion in the right lobe of liver. She underwent marginal excision of the T3 tumor with T2-4 pedicular screw fixation in March 2017, then right hemi-hepatectomy was performed to remove the liver lesion in June 2017. Both of the lesions were confirmed to be a metastatic and malignant tumor after surgery. The literature lacks randomized controlled trials and large studies that define the natural history of malignant solitary fibrous tumors and recommendations of precise management plan for the disease. However, the best choice for treatment is gross total resection, which probably provide the optimal treatment to achieve long-term disease-free survival. Frontiers Media S.A. 2020-12-03 /pmc/articles/PMC7744481/ /pubmed/33344498 http://dx.doi.org/10.3389/fsurg.2020.570582 Text en Copyright © 2020 Mao, Zhou, Huang, Yan, Hu, Yin, Zhao and Song. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Mao, Min
Zhou, Lei
Huang, Chaojun
Yan, Xudong
Hu, Shuo
Yin, Huabin
Zhao, Qinghua
Song, Dianwen
Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
title Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
title_full Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
title_fullStr Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
title_full_unstemmed Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
title_short Case Report: A Malignant Liver and Thoracic Solitary Fibrous Tumor: A 10-Year Journey From the Brain to the Liver and the Spine
title_sort case report: a malignant liver and thoracic solitary fibrous tumor: a 10-year journey from the brain to the liver and the spine
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744481/
https://www.ncbi.nlm.nih.gov/pubmed/33344498
http://dx.doi.org/10.3389/fsurg.2020.570582
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