Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor

The formation of dentin and enamel matrix depends on reciprocal interactions between epithelial-mesenchymal cells. To assess the role of mitochondrial function in amelogenesis and dentinogenesis, we studied postnatal incisor development in K320E-Twinkle(Epi) mice. In these mice, a loss of mitochondr...

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Detalles Bibliográficos
Autores principales: Imhof, Thomas, Rosenblatt, Katharina, Pryymachuk, Galyna, Weiland, Daniela, Noetzel, Nicolas, Deschner, James, Baris, Olivier R., Kimoloi, Sammy, Koch, Manuel, Wiesner, Rudolf J., Korkmaz, Yüksel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744519/
https://www.ncbi.nlm.nih.gov/pubmed/33328493
http://dx.doi.org/10.1038/s41598-020-77954-7

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