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Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, par...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744613/ https://www.ncbi.nlm.nih.gov/pubmed/33343398 http://dx.doi.org/10.3389/fphys.2020.602748 |
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author | Yang, Yong Ryoul Kwon, Ki-Sun |
author_facet | Yang, Yong Ryoul Kwon, Ki-Sun |
author_sort | Yang, Yong Ryoul |
collection | PubMed |
description | Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites via metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise. |
format | Online Article Text |
id | pubmed-7744613 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77446132020-12-18 Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits Yang, Yong Ryoul Kwon, Ki-Sun Front Physiol Physiology Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites via metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise. Frontiers Media S.A. 2020-12-03 /pmc/articles/PMC7744613/ /pubmed/33343398 http://dx.doi.org/10.3389/fphys.2020.602748 Text en Copyright © 2020 Yang and Kwon. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Yang, Yong Ryoul Kwon, Ki-Sun Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
title | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
title_full | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
title_fullStr | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
title_full_unstemmed | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
title_short | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
title_sort | potential roles of exercise-induced plasma metabolites linking exercise to health benefits |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744613/ https://www.ncbi.nlm.nih.gov/pubmed/33343398 http://dx.doi.org/10.3389/fphys.2020.602748 |
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