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Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits

Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, par...

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Autores principales: Yang, Yong Ryoul, Kwon, Ki-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744613/
https://www.ncbi.nlm.nih.gov/pubmed/33343398
http://dx.doi.org/10.3389/fphys.2020.602748
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author Yang, Yong Ryoul
Kwon, Ki-Sun
author_facet Yang, Yong Ryoul
Kwon, Ki-Sun
author_sort Yang, Yong Ryoul
collection PubMed
description Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites via metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise.
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spelling pubmed-77446132020-12-18 Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits Yang, Yong Ryoul Kwon, Ki-Sun Front Physiol Physiology Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites via metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise. Frontiers Media S.A. 2020-12-03 /pmc/articles/PMC7744613/ /pubmed/33343398 http://dx.doi.org/10.3389/fphys.2020.602748 Text en Copyright © 2020 Yang and Kwon. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Yang, Yong Ryoul
Kwon, Ki-Sun
Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
title Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
title_full Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
title_fullStr Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
title_full_unstemmed Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
title_short Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
title_sort potential roles of exercise-induced plasma metabolites linking exercise to health benefits
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744613/
https://www.ncbi.nlm.nih.gov/pubmed/33343398
http://dx.doi.org/10.3389/fphys.2020.602748
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