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BSA-Stabilized Mesoporous Organosilica Nanoparticles Reversed Chemotherapy Resistance of Anaplastic Thyroid Cancer by Increasing Drug Uptake and Reducing Cellular Efflux

Anaplastic thyroid cancer (ATC) is a highly aggressive and the most lethal type of thyroid cancer. The standard-of-care for unresectable ATC is radiotherapy and chemotherapy, usually based on doxorubicin (Dox). However, most patients develop resistance shortly after treatment. To overcome the drug r...

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Detalles Bibliográficos
Autores principales:	Han, Xiao, Xu, Xiaoquan, Tang, Yuxia, Zhu, Feipeng, Tian, Ying, Liu, Wei, He, Doudou, Lu, Guangming, Gu, Yunfei, Wang, Shouju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744685/ https://www.ncbi.nlm.nih.gov/pubmed/33344508 http://dx.doi.org/10.3389/fmolb.2020.610084

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