Cargando…

Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel

SthK, a cyclic nucleotide-modulated ion channel from Spirochaeta thermophila, activates slowly upon cAMP increase. This is reminiscent of the slow, cAMP-induced activation reported for the hyperpolarization-activated and cyclic nucleotide-gated channel HCN2 in the family of so-called pacemaker chann...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmidpeter, Philipp A. M., Rheinberger, Jan, Nimigean, Crina M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744796/ https://www.ncbi.nlm.nih.gov/pubmed/33328472 http://dx.doi.org/10.1038/s41467-020-20104-4

Ejemplares similares

Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures
por: Rheinberger, Jan, et al.
Publicado: (2018)

Ligand binding and activation properties of the purified bacterial cyclic nucleotide–gated channel SthK
por: Schmidpeter, Philipp A.M., et al.
Publicado: (2018)

An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel
por: Marchesi, Arin, et al.
Publicado: (2018)

Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel
por: Gao, Xiaolong, et al.
Publicado: (2022)

A Cyclic Nucleotide Modulated Prokaryotic K(+) Channel
por: Nimigean, Crina M., et al.
Publicado: (2004)

Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel
por: Tong, Ailing, et al.
Publicado: (2019)

The gating mechanism in cyclic nucleotide-gated ion channels
por: Mazzolini, Monica, et al.
Publicado: (2018)

Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1
por: Schmidpeter, Philipp A. M., et al.
Publicado: (2023)

Cooperativity in cyclic nucleotide-gated ion channels
por: Pugh EN,
Publicado: (1996)

Influence of Permeant Ions on Gating in Cyclic Nucleotide–gated Channels
por: Holmgren, Miguel
Publicado: (2003)

Mechanism of Inhibition of Cyclic Nucleotide–Gated Ion Channels by Diacylglycerol
por: Crary, Jennifer I., et al.
Publicado: (2000)

Modification of Cyclic Nucleotide–Gated Ion Channels by Ultraviolet Light
por: Middendorf, Thomas R., et al.
Publicado: (2000)

Calcium-dependent Gating of MthK, a Prokaryotic Potassium Channel
por: Zadek, Brittany, et al.
Publicado: (2006)

Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels
por: Rangl, Martina, et al.
Publicado: (2016)

Calcium ions open a selectivity filter gate during activation of the MthK potassium channel
por: Posson, David J., et al.
Publicado: (2015)

Ion Channel Structure and the Promise of Bacteria: Cyclic Nucleotide-Gated Channels in the Queue
por: Karpen, Jeffrey W.
Publicado: (2004)

Pseudechetoxin Binds to the Pore Turret of Cyclic Nucleotide–gated Ion Channels
por: Brown, R. Lane, et al.
Publicado: (2003)

Origins of ion selectivity in potassium channels from the perspective of channel block
por: Nimigean, Crina M., et al.
Publicado: (2011)

Dysfunctional Hyperpolarization-Activated Cyclic Nucleotide-gated Ion Channels in Cardiac Diseases
por: Zhao, Xiaoqi, et al.
Publicado: (2016)

Transfected Cyclic Nucleotide–Gated Channels as Biosensors
por: Pugh, Edward N.
Publicado: (2000)

C-Linker of Cyclic Nucleotide–gated Channels Controls Coupling of Ligand Binding to Channel Gating
por: Paoletti, Pierre, et al.
Publicado: (1999)

Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1
por: Kowal, Julia, et al.
Publicado: (2014)

Importance of the αC-helix in the cyclic nucleotide binding domain for the stable channel regulation and function of cyclic nucleotide gated ion channels in Arabidopsis
por: Chin, Kimberley, et al.
Publicado: (2010)

Cyclic Nucleotide-gated Ion Channels in Rod Photoreceptors Are Protected from Retinoid Inhibition
por: He, Quanhua, et al.
Publicado: (2006)

The Complex Story of Plant Cyclic Nucleotide-Gated Channels
por: Jarratt-Barnham, Edwin, et al.
Publicado: (2021)

Effects of Ultraviolet Modification on the Gating Energetics of Cyclic Nucleotide–Gated Channels
por: Middendorf, Thomas R., et al.
Publicado: (2000)

The voltage-dependent gate in MthK potassium channels is located at the selectivity filter
por: Posson, David J., et al.
Publicado: (2012)

Mechanism of Tetracaine Block of Cyclic Nucleotide-gated Channels
por: Fodor, Anthony A., et al.
Publicado: (1997)

Retinal Cyclic Nucleotide-Gated Channel Regulation by Calmodulin
por: Bej, Aritra, et al.
Publicado: (2022)

The β Subunit Increases the Ca(2+) Sensitivity of Large Conductance Ca(2+)-activated Potassium Channels by Retaining the Gating in the Bursting States
por: Nimigean, Crina M., et al.
Publicado: (1999)

Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels
por: Shuart, Noah G., et al.
Publicado: (2011)

Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide–gated ion channel
por: Ng, Leo C.T., et al.
Publicado: (2019)

All-trans-retinal Is a Closed-state Inhibitor of Rod Cyclic Nucleotide–gated Ion Channels
por: McCabe, Sarah L., et al.
Publicado: (2004)

“Light” Reading: Targeting Tryptophans in Cyclic Nucleotide–Gated Channels
por: Gordon, Sharona E.
Publicado: (2000)

Mechanism of Allosteric Modulation of Rod Cyclic Nucleotide–gated Channels
por: Sunderman, Elizabeth R., et al.
Publicado: (1999)

Tuning Ca(2+) Permeation in Cyclic Nucleotide–gated Channels
por: Frings, Stephan
Publicado: (1999)

Effects of Cyclic Nucleotide-Gated Channels in Vestibular Nuclear Neurons
por: Heo, Tag, et al.
Publicado: (2011)

Role of Cyclic Nucleotide Gated Channels in Stress Management in Plants
por: Jha, Saroj K., et al.
Publicado: (2016)

Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy
por: Michalakis, Stylianos, et al.
Publicado: (2018)

Cyclic Nucleotide-gated Channels on the Flagellum Control Ca(2+) Entry into Sperm
por: Wiesner, Burkhard, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_3ghmmo488hhde563vko9gp4ev5