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Hydrogen sulfide releasing molecule MZe786 inhibits soluble Flt-1 and prevents preeclampsia in a refined RUPP mouse model
An imbalance in angiogenic growth factors and poor utero-placental perfusion are strongly associated with preeclampsia. The reduced utero-placental perfusion (RUPP) model that mimics insufficient placental perfusion is used to study preeclampsia. The aim of this study was to develop a refined RUPP m...
Autores principales: | Saif, Jaimy, Ahmad, Shakil, Rezai, Homira, Litvinova, Karina, Sparatore, Anna, Alzahrani, Faisal A., Wang, Keqing, Ahmed, Asif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744945/ https://www.ncbi.nlm.nih.gov/pubmed/33321463 http://dx.doi.org/10.1016/j.redox.2020.101814 |
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