Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling

Cockayne syndrome (CS) is a rare premature aging disease, most commonly caused by mutations of the genes encoding the CSA or CSB proteins. CS patients display cachectic dwarfism and severe neurological manifestations and have an average life expectancy of 12 years. The CS proteins are involved in tr...

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Detalles Bibliográficos
Autores principales: Okur, Mustafa N., Fang, Evandro F., Fivenson, Elayne M., Tiwari, Vinod, Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744955/
https://www.ncbi.nlm.nih.gov/pubmed/33166073
http://dx.doi.org/10.1111/acel.13268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744955/
https://www.ncbi.nlm.nih.gov/pubmed/33166073
http://dx.doi.org/10.1111/acel.13268

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