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Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer

DNA repair gene aberrations (GAs) occur in several cancers, may be prognostic and are actionable. We investigated the frequency of DNA repair GAs in gallbladder cancer (GBC), association with tumor mutational burden (TMB), microsatellite instability (MSI), programmed cell death protein 1 (PD-1), and...

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Detalles Bibliográficos
Autores principales:	Abdel-Wahab, Reham, Yap, Timothy A., Madison, Russell, Pant, Shubham, Cooke, Matthew, Wang, Kai, Zhao, Haitao, Bekaii-Saab, Tanios, Karatas, Elif, Kwong, Lawrence N., Meric-Bernstam, Funda, Borad, Mitesh, Javle, Milind
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745036/ https://www.ncbi.nlm.nih.gov/pubmed/33328484 http://dx.doi.org/10.1038/s41598-020-77939-6

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