Cargando…

GD2-specific chimeric antigen receptor-modified T cells targeting retinoblastoma – assessing tumor and T cell interaction

A novel disialoganglioside 2 (GD2)-specific chimeric antigen receptor (CAR)-modified T cell therapy against retinoblastoma (RB) were generated. GD2-CAR consists of a single-chain variable fragment (scFv) derived from a monoclonal antibody, hu3F8, that is linked with the cytoplasmic signaling domains...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sujjitjoon, Jatuporn, Sayour, Elias, Tsao, Shih-Ting, Uiprasertkul, Mongkol, Sanpakit, Kleebsabai, Buaboonnam, Jassada, Yenchitsomanus, Pa-thai, Atchaneeyasakul, La-ongsri, Chang, Lung-Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745061/ https://www.ncbi.nlm.nih.gov/pubmed/33321428 http://dx.doi.org/10.1016/j.tranon.2020.100971

Ejemplares similares

Dopachrome tautomerase is a retinoblastoma-specific gene, and its proximal promoter is preferentially active in human retinoblastoma cells
por: Moolsuwan, Kanya, et al.
Publicado: (2022)

Anti-mucin 1 chimeric antigen receptor T cells for adoptive T cell therapy of cholangiocarcinoma
por: Supimon, Kamonlapat, et al.
Publicado: (2021)

Chimeric Antigen Receptor T Cells Targeting Integrin αvβ6 Expressed on Cholangiocarcinoma Cells
por: Phanthaphol, Nattaporn, et al.
Publicado: (2021)

Antifungal Prophylaxis with Posaconazole versus Fluconazole in Children with Neutropenia Following Allogeneic Hematopoietic Stem Cell Transplantation: Single Center Experience
por: Takpradit, Chayamon, et al.
Publicado: (2021)

Long-Term Effectiveness, Safety, and Tolerability of Twice-Daily Dosing with Deferasirox in Children with Transfusion-Dependent Thalassemias Unresponsive to Standard Once-Daily Dosing
por: Buaboonnam, Jassada, et al.
Publicado: (2021)

Antitumor activity of T cells secreting αCD133-αCD3 bispecific T-cell engager against cholangiocarcinoma
por: Sangsuwannukul, Thanich, et al.
Publicado: (2022)

Hemoglobin H Disease and Growth: A Comparative Study of DHbH and NDHbH Patients
por: Hunnuan, Issanun, et al.
Publicado: (2023)

Outcomes of Overt and Non-overt Disseminated Intravascular Coagulation Using the ISTH DIC Scoring System in Children: A Single-Center Study
por: Buaboonnam, Jassada, et al.
Publicado: (2023)

Estradiol Prevents High Glucose-Induced β-cell Apoptosis by Decreased BTG2 Expression
por: Kooptiwut, Suwattanee, et al.
Publicado: (2018)

Invasive Fungal Diseases in Children with Acute Leukemia and Severe Aplastic Anemia
por: Supatharawanich, Sutatta, et al.
Publicado: (2021)

ITPA Polymorphisms and the Incidence of Toxicities in Children with Acute Lymphoblastic Leukemia
por: Svasdisant, Patpetra, et al.
Publicado: (2023)

Novel Adiponectin Variants Identified in Type 2 Diabetic Patients Reveal Multimerization and Secretion Defects
por: Jungtrakoon, Prapaporn, et al.
Publicado: (2011)

Intravitreal autologous mesenchymal stem cell transplantation: a non-randomized phase I clinical trial in patients with retinitis pigmentosa
por: Tuekprakhon, Aekkachai, et al.
Publicado: (2021)

Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains
por: Wutti-in, Yupanun, et al.
Publicado: (2022)

Combination gemcitabine and PD-L1xCD3 bispecific T cell engager (BiTE) enhances T lymphocyte cytotoxicity against cholangiocarcinoma cells
por: Wathikthinnakon, Methi, et al.
Publicado: (2022)

Effect of surgical simulation training on the complication rate of resident-performed phacoemulsification
por: Montrisuksirikun, Chinnapat, et al.
Publicado: (2022)

Epidemiology of Pediatric Open Globe Injuries in a University Hospital in Thailand
por: Saksiriwutto, Piangporn, et al.
Publicado: (2021)

Efficacy of cultivated corneal epithelial stem cells for ocular surface reconstruction
por: Prabhasawat, Pinnita, et al.
Publicado: (2012)

Run-on mutation in the PAX6 gene and chorioretinal degeneration in autosomal dominant aniridia
por: Aggarwal, Shagun, et al.
Publicado: (2011)

Well-Circumscribed Intramuscular Lipoma of Superior Rectus Muscle
por: Tangtammaruk, Phantaraporn, et al.
Publicado: (2023)

Genistein Sensitizes Human Cholangiocarcinoma Cell Lines to Be Susceptible to Natural Killer Cells
por: Chiawpanit, Chutipa, et al.
Publicado: (2022)

CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing
por: Andersch, Lena, et al.
Publicado: (2019)

GD2-specific chimeric antigen receptor-modified T cells for the treatment of refractory and/or recurrent neuroblastoma in pediatric patients
por: Yu, Lihua, et al.
Publicado: (2021)

Activation of cytotoxic T lymphocytes by self-differentiated myeloid-derived dendritic cells for killing breast cancer cells expressing folate receptor alpha protein
por: Luangwattananun, Piriya, et al.
Publicado: (2022)

Rare Co-Occurrence of Visual Snow in a Female Carrier With RPGR(ORF15)-Associated Retinal Disorder
por: Tuekprakhon, Aekkachai, et al.
Publicado: (2021)

Genotypic and phenotypic profiles of EYS gene-related retinitis pigmentosa: a retrospective study
por: Suvannaboon, Ragkit, et al.
Publicado: (2022)

Targeting disialoganglioside GD2 with chimeric antigen receptor-redirected T cells in lung cancer
por: Reppel, Loïc, et al.
Publicado: (2022)

Unusual non-nanophthalmic uveal effusion syndrome with histologically normal scleral architecture: a case report
por: Kaewsangthong, Kasama, et al.
Publicado: (2020)

Estrogen attenuates AGTR1 expression to reduce pancreatic β-cell death from high glucose
por: Kooptiwut, Suwattanee, et al.
Publicado: (2017)

Cytolytic Activity of Effector T-lymphocytes Against Hepatocellular Carcinoma is Improved by Dendritic Cells Pulsed with Pooled Tumor Antigens
por: Chieochansin, Thaweesak, et al.
Publicado: (2019)

Orbital Infection by Saksenaea vasiformis in an Immunocompetent Host
por: Lumyongsatien, Mingkwan, et al.
Publicado: (2020)

Cordycepin Sensitizes Cholangiocarcinoma Cells to Be Killed by Natural Killer-92 (NK-92) Cells
por: Panwong, Suthida, et al.
Publicado: (2021)

Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis
por: Suksri, Kanchana, et al.
Publicado: (2022)

Anti-Proliferative Effects of Compound A and Its Effect in Combination with Cisplatin in Cholangiocarcinoma Cells
por: Junking, Mutita, et al.
Publicado: (2020)

Rare presentation of intractable tuberculous panophthalmitis with intraocular and intraorbital abscesses: a case report
por: Boonsopon, Sutasinee, et al.
Publicado: (2017)

Treatment outcomes of high-dose chemotherapy plus stem cell rescue in high-risk neuroblastoma patients in Thailand
por: Suwannaying, Kunanya, et al.
Publicado: (2022)

Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors
por: Sawasdee, Nunghathai, et al.
Publicado: (2022)

Bispecific antibody does not induce T-cell death mediated by chimeric antigen receptor against disialoganglioside GD2
por: Hoseini, Sayed Shahabuddin, et al.
Publicado: (2017)

GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells
por: Seitz, Christian M., et al.
Publicado: (2019)

Crocetin Improves Dengue Virus-Induced Liver Injury
por: Sreekanth, Gopinathan Pillai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kmr1glmq32q6km101bg25vuqq6