Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19

BACKGROUND: Severe coronavirus disease 2019 (Covid-19) is associated with dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, plus remdesivir are not known. METHODS: We conducted a double-blind, randomized, placebo-controlled trial evaluating b...

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Detalles Bibliográficos
Autores principales: Kalil, Andre C., Patterson, Thomas F., Mehta, Aneesh K., Tomashek, Kay M., Wolfe, Cameron R., Ghazaryan, Varduhi, Marconi, Vincent C., Ruiz-Palacios, Guillermo M., Hsieh, Lanny, Kline, Susan, Tapson, Victor, Iovine, Nicole M., Jain, Mamta K., Sweeney, Daniel A., El Sahly, Hana M., Branche, Angela R., Regalado Pineda, Justino, Lye, David C., Sandkovsky, Uriel, Luetkemeyer, Anne F., Cohen, Stuart H., Finberg, Robert W., Jackson, Patrick E.H., Taiwo, Babafemi, Paules, Catherine I., Arguinchona, Henry, Goepfert, Paul, Ahuja, Neera, Frank, Maria, Oh, Myoung-don, Kim, Eu S., Tan, Seow Y., Mularski, Richard A., Nielsen, Henrik, Ponce, Philip O., Taylor, Barbara S., Larson, LuAnn, Rouphael, Nadine G., Saklawi, Youssef, Cantos, Valeria D., Ko, Emily R., Engemann, John J., Amin, Alpesh N., Watanabe, Miki, Billings, Joanne, Elie, Marie-Carmelle, Davey, Richard T., Burgess, Timothy H., Ferreira, Jennifer, Green, Michelle, Makowski, Mat, Cardoso, Anabela, de Bono, Stephanie, Bonnett, Tyler, Proschan, Michael, Deye, Gregory A., Dempsey, Walla, Nayak, Seema U., Dodd, Lori E., Beigel, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745180/
https://www.ncbi.nlm.nih.gov/pubmed/33306283
http://dx.doi.org/10.1056/NEJMoa2031994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745180/
https://www.ncbi.nlm.nih.gov/pubmed/33306283
http://dx.doi.org/10.1056/NEJMoa2031994

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