Cargando…
Ion Transfer Voltammetry with an Electrochemical Pen
[Image: see text] We present a new electrochemical system that combines paper-based sensing and ion-transfer voltammetry, bringing the latter a step closer toward point-of-care applications. Studies at the interface between two immiscible electrolyte solutions (ITIES) are often performed to detect r...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745201/ https://www.ncbi.nlm.nih.gov/pubmed/33259187 http://dx.doi.org/10.1021/acs.analchem.0c03530 |
_version_ | 1783624566051962880 |
---|---|
author | Podrażka, Marta Witkowska Nery, Emilia Henares, Terence G. Jönsson-Niedziółka, Martin Arrigan, Damien W. M. |
author_facet | Podrażka, Marta Witkowska Nery, Emilia Henares, Terence G. Jönsson-Niedziółka, Martin Arrigan, Damien W. M. |
author_sort | Podrażka, Marta |
collection | PubMed |
description | [Image: see text] We present a new electrochemical system that combines paper-based sensing and ion-transfer voltammetry, bringing the latter a step closer toward point-of-care applications. Studies at the interface between two immiscible electrolyte solutions (ITIES) are often performed to detect redox-inactive species; unfortunately, due to the inherent instability of the interface, it is rather poorly explored outside specialized laboratories. Here, we address this limitation by combining a pen-like device containing the gelled organic phase with a paper-supported aqueous phase. This combination makes the system more user-friendly, potentially low-cost, and easy to assemble. We show the applicability of the new cell to analyze both simple and ionophore-facilitated transfer of ions and proteins, preconcentration of species, and analysis of mixtures through combination with paper chromatography. The native ion content of the paper also enabled measurements without added electrolytes. Those studies could broaden the scope for the application of the label-free electrochemical detection of nonredox-active species at points-of-need. |
format | Online Article Text |
id | pubmed-7745201 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American
Chemical
Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-77452012020-12-17 Ion Transfer Voltammetry with an Electrochemical Pen Podrażka, Marta Witkowska Nery, Emilia Henares, Terence G. Jönsson-Niedziółka, Martin Arrigan, Damien W. M. Anal Chem [Image: see text] We present a new electrochemical system that combines paper-based sensing and ion-transfer voltammetry, bringing the latter a step closer toward point-of-care applications. Studies at the interface between two immiscible electrolyte solutions (ITIES) are often performed to detect redox-inactive species; unfortunately, due to the inherent instability of the interface, it is rather poorly explored outside specialized laboratories. Here, we address this limitation by combining a pen-like device containing the gelled organic phase with a paper-supported aqueous phase. This combination makes the system more user-friendly, potentially low-cost, and easy to assemble. We show the applicability of the new cell to analyze both simple and ionophore-facilitated transfer of ions and proteins, preconcentration of species, and analysis of mixtures through combination with paper chromatography. The native ion content of the paper also enabled measurements without added electrolytes. Those studies could broaden the scope for the application of the label-free electrochemical detection of nonredox-active species at points-of-need. American Chemical Society 2020-12-01 2020-12-15 /pmc/articles/PMC7745201/ /pubmed/33259187 http://dx.doi.org/10.1021/acs.analchem.0c03530 Text en © 2020 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited. |
spellingShingle | Podrażka, Marta Witkowska Nery, Emilia Henares, Terence G. Jönsson-Niedziółka, Martin Arrigan, Damien W. M. Ion Transfer Voltammetry with an Electrochemical Pen |
title | Ion Transfer Voltammetry with an Electrochemical Pen |
title_full | Ion Transfer Voltammetry with an Electrochemical Pen |
title_fullStr | Ion Transfer Voltammetry with an Electrochemical Pen |
title_full_unstemmed | Ion Transfer Voltammetry with an Electrochemical Pen |
title_short | Ion Transfer Voltammetry with an Electrochemical Pen |
title_sort | ion transfer voltammetry with an electrochemical pen |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745201/ https://www.ncbi.nlm.nih.gov/pubmed/33259187 http://dx.doi.org/10.1021/acs.analchem.0c03530 |
work_keys_str_mv | AT podrazkamarta iontransfervoltammetrywithanelectrochemicalpen AT witkowskaneryemilia iontransfervoltammetrywithanelectrochemicalpen AT henaresterenceg iontransfervoltammetrywithanelectrochemicalpen AT jonssonniedziołkamartin iontransfervoltammetrywithanelectrochemicalpen AT arrigandamienwm iontransfervoltammetrywithanelectrochemicalpen |