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Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Communications and Publications Division (CPD) of the IFCC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745297/ https://www.ncbi.nlm.nih.gov/pubmed/33376475 |
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author | van Heerden, Marli Mabuza, Dineo |
author_facet | van Heerden, Marli Mabuza, Dineo |
author_sort | van Heerden, Marli |
collection | PubMed |
description | Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on galactorrhoea following burn injury to the chest wall. We report a case of an adult female patient who sustained hot water burns to her torso. Following the second skin graft failure, galactorrhoea was noted and investigated. Hyperprolactinaemia was found with normal renal and thyroid function. There were no abnormalities detected on the hormones in the hypothalamic pituitary axis and MRI. Hyperprolactinaemia was attributed to chest wall injuries causing pathological stimulation of the neural suckling reflex. The patient was treated with dopamine agonists for one month and the galactorrhoea disappeared. Treatment was discontinued on discharge and the prolactin levels remained normal upon follow-up visit to the clinic. |
format | Online Article Text |
id | pubmed-7745297 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Communications and Publications Division (CPD) of the IFCC |
record_format | MEDLINE/PubMed |
spelling | pubmed-77452972020-12-28 Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns van Heerden, Marli Mabuza, Dineo EJIFCC Case Report Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on galactorrhoea following burn injury to the chest wall. We report a case of an adult female patient who sustained hot water burns to her torso. Following the second skin graft failure, galactorrhoea was noted and investigated. Hyperprolactinaemia was found with normal renal and thyroid function. There were no abnormalities detected on the hormones in the hypothalamic pituitary axis and MRI. Hyperprolactinaemia was attributed to chest wall injuries causing pathological stimulation of the neural suckling reflex. The patient was treated with dopamine agonists for one month and the galactorrhoea disappeared. Treatment was discontinued on discharge and the prolactin levels remained normal upon follow-up visit to the clinic. The Communications and Publications Division (CPD) of the IFCC 2020-11-20 /pmc/articles/PMC7745297/ /pubmed/33376475 Text en Copyright © 2020 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This is a Platinum Open Access Journal distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report van Heerden, Marli Mabuza, Dineo Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns |
title | Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns |
title_full | Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns |
title_fullStr | Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns |
title_full_unstemmed | Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns |
title_short | Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns |
title_sort | galactorrhoea and hyperprolactinaemia in a non-pregnant female with burns |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745297/ https://www.ncbi.nlm.nih.gov/pubmed/33376475 |
work_keys_str_mv | AT vanheerdenmarli galactorrhoeaandhyperprolactinaemiainanonpregnantfemalewithburns AT mabuzadineo galactorrhoeaandhyperprolactinaemiainanonpregnantfemalewithburns |