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Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns

Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on...

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Autores principales: van Heerden, Marli, Mabuza, Dineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745297/
https://www.ncbi.nlm.nih.gov/pubmed/33376475
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author van Heerden, Marli
Mabuza, Dineo
author_facet van Heerden, Marli
Mabuza, Dineo
author_sort van Heerden, Marli
collection PubMed
description Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on galactorrhoea following burn injury to the chest wall. We report a case of an adult female patient who sustained hot water burns to her torso. Following the second skin graft failure, galactorrhoea was noted and investigated. Hyperprolactinaemia was found with normal renal and thyroid function. There were no abnormalities detected on the hormones in the hypothalamic pituitary axis and MRI. Hyperprolactinaemia was attributed to chest wall injuries causing pathological stimulation of the neural suckling reflex. The patient was treated with dopamine agonists for one month and the galactorrhoea disappeared. Treatment was discontinued on discharge and the prolactin levels remained normal upon follow-up visit to the clinic.
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spelling pubmed-77452972020-12-28 Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns van Heerden, Marli Mabuza, Dineo EJIFCC Case Report Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on galactorrhoea following burn injury to the chest wall. We report a case of an adult female patient who sustained hot water burns to her torso. Following the second skin graft failure, galactorrhoea was noted and investigated. Hyperprolactinaemia was found with normal renal and thyroid function. There were no abnormalities detected on the hormones in the hypothalamic pituitary axis and MRI. Hyperprolactinaemia was attributed to chest wall injuries causing pathological stimulation of the neural suckling reflex. The patient was treated with dopamine agonists for one month and the galactorrhoea disappeared. Treatment was discontinued on discharge and the prolactin levels remained normal upon follow-up visit to the clinic. The Communications and Publications Division (CPD) of the IFCC 2020-11-20 /pmc/articles/PMC7745297/ /pubmed/33376475 Text en Copyright © 2020 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This is a Platinum Open Access Journal distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
van Heerden, Marli
Mabuza, Dineo
Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
title Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
title_full Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
title_fullStr Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
title_full_unstemmed Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
title_short Galactorrhoea and Hyperprolactinaemia in a Non-Pregnant Female with Burns
title_sort galactorrhoea and hyperprolactinaemia in a non-pregnant female with burns
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745297/
https://www.ncbi.nlm.nih.gov/pubmed/33376475
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