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Experimentally Validated QSAR Model for Surface pK(a) Prediction of Heterolipids Having Potential as Delivery Materials for Nucleic Acid Therapeutics

[Image: see text] The application of lipid-based drug delivery technologies for bioavailability enhancement of drugs has led to many successful products in the market for clinical use. Recent studies on amine-containing heterolipid-based synthetic vectors for delivery of siRNA have witnessed the Uni...

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Detalles Bibliográficos
Autores principales: Dhumal, Dinesh M., Patil, Pankaj D., Kulkarni, Raghavendra V., Akamanchi, Krishnacharya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745400/
https://www.ncbi.nlm.nih.gov/pubmed/33344856
http://dx.doi.org/10.1021/acsomega.0c04931

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