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Complement controls the immune synapse and tumors control complement

The synapses between immune cells and their targets are 150 Å wide. They regulate immune cell responses (IRs) to cognate antigens. Here, I outline a potential mechanism for self-nonself discrimination based on the C3d and iC3b proteolytic fragments of complement protein C3. The proposed C3 checkpoin...

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Detalles Bibliográficos
Autor principal: Herbert, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745530/
https://www.ncbi.nlm.nih.gov/pubmed/33323465
http://dx.doi.org/10.1136/jitc-2020-001712

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