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Atypical painless vision loss in a patient with granulomatosis with polyangiitis

Vasculitis is a common cause of vision loss, and typically painful. In giant cell arteritis, the most common primary vasculitis in adults, we see elevated inflammatory markers, granulomatous inflammation, and associated headache or scalp tenderness. Vision loss caused by granulomatous with polyangii...

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Autores principales: Nelson, Patricia C., Kunam, Vamsi, Prospero Ponce, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745643/
https://www.ncbi.nlm.nih.gov/pubmed/33384913
http://dx.doi.org/10.3205/oc000173
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author Nelson, Patricia C.
Kunam, Vamsi
Prospero Ponce, Claudia
author_facet Nelson, Patricia C.
Kunam, Vamsi
Prospero Ponce, Claudia
author_sort Nelson, Patricia C.
collection PubMed
description Vasculitis is a common cause of vision loss, and typically painful. In giant cell arteritis, the most common primary vasculitis in adults, we see elevated inflammatory markers, granulomatous inflammation, and associated headache or scalp tenderness. Vision loss caused by granulomatous with polyangiitis (GPA) is rare and typically associated with pain and orbital findings. Our patient presented for shortness of breath and painless vision loss without orbital inflammation or neural enhancement and a normal fundus exam, suggesting posterior ischemic optic neuropathy. Collaboration amongst sub-specialties and obtaining tissue samples are key to diagnosing granulomatosis with polyangiitis to ensure timely treatment of this fatal and blinding disease.
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spelling pubmed-77456432020-12-30 Atypical painless vision loss in a patient with granulomatosis with polyangiitis Nelson, Patricia C. Kunam, Vamsi Prospero Ponce, Claudia GMS Ophthalmol Cases Article Vasculitis is a common cause of vision loss, and typically painful. In giant cell arteritis, the most common primary vasculitis in adults, we see elevated inflammatory markers, granulomatous inflammation, and associated headache or scalp tenderness. Vision loss caused by granulomatous with polyangiitis (GPA) is rare and typically associated with pain and orbital findings. Our patient presented for shortness of breath and painless vision loss without orbital inflammation or neural enhancement and a normal fundus exam, suggesting posterior ischemic optic neuropathy. Collaboration amongst sub-specialties and obtaining tissue samples are key to diagnosing granulomatosis with polyangiitis to ensure timely treatment of this fatal and blinding disease. German Medical Science GMS Publishing House 2020-12-15 /pmc/articles/PMC7745643/ /pubmed/33384913 http://dx.doi.org/10.3205/oc000173 Text en Copyright © 2020 Nelson et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Nelson, Patricia C.
Kunam, Vamsi
Prospero Ponce, Claudia
Atypical painless vision loss in a patient with granulomatosis with polyangiitis
title Atypical painless vision loss in a patient with granulomatosis with polyangiitis
title_full Atypical painless vision loss in a patient with granulomatosis with polyangiitis
title_fullStr Atypical painless vision loss in a patient with granulomatosis with polyangiitis
title_full_unstemmed Atypical painless vision loss in a patient with granulomatosis with polyangiitis
title_short Atypical painless vision loss in a patient with granulomatosis with polyangiitis
title_sort atypical painless vision loss in a patient with granulomatosis with polyangiitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745643/
https://www.ncbi.nlm.nih.gov/pubmed/33384913
http://dx.doi.org/10.3205/oc000173
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