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Atypical painless vision loss in a patient with granulomatosis with polyangiitis
Vasculitis is a common cause of vision loss, and typically painful. In giant cell arteritis, the most common primary vasculitis in adults, we see elevated inflammatory markers, granulomatous inflammation, and associated headache or scalp tenderness. Vision loss caused by granulomatous with polyangii...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745643/ https://www.ncbi.nlm.nih.gov/pubmed/33384913 http://dx.doi.org/10.3205/oc000173 |
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author | Nelson, Patricia C. Kunam, Vamsi Prospero Ponce, Claudia |
author_facet | Nelson, Patricia C. Kunam, Vamsi Prospero Ponce, Claudia |
author_sort | Nelson, Patricia C. |
collection | PubMed |
description | Vasculitis is a common cause of vision loss, and typically painful. In giant cell arteritis, the most common primary vasculitis in adults, we see elevated inflammatory markers, granulomatous inflammation, and associated headache or scalp tenderness. Vision loss caused by granulomatous with polyangiitis (GPA) is rare and typically associated with pain and orbital findings. Our patient presented for shortness of breath and painless vision loss without orbital inflammation or neural enhancement and a normal fundus exam, suggesting posterior ischemic optic neuropathy. Collaboration amongst sub-specialties and obtaining tissue samples are key to diagnosing granulomatosis with polyangiitis to ensure timely treatment of this fatal and blinding disease. |
format | Online Article Text |
id | pubmed-7745643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-77456432020-12-30 Atypical painless vision loss in a patient with granulomatosis with polyangiitis Nelson, Patricia C. Kunam, Vamsi Prospero Ponce, Claudia GMS Ophthalmol Cases Article Vasculitis is a common cause of vision loss, and typically painful. In giant cell arteritis, the most common primary vasculitis in adults, we see elevated inflammatory markers, granulomatous inflammation, and associated headache or scalp tenderness. Vision loss caused by granulomatous with polyangiitis (GPA) is rare and typically associated with pain and orbital findings. Our patient presented for shortness of breath and painless vision loss without orbital inflammation or neural enhancement and a normal fundus exam, suggesting posterior ischemic optic neuropathy. Collaboration amongst sub-specialties and obtaining tissue samples are key to diagnosing granulomatosis with polyangiitis to ensure timely treatment of this fatal and blinding disease. German Medical Science GMS Publishing House 2020-12-15 /pmc/articles/PMC7745643/ /pubmed/33384913 http://dx.doi.org/10.3205/oc000173 Text en Copyright © 2020 Nelson et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Nelson, Patricia C. Kunam, Vamsi Prospero Ponce, Claudia Atypical painless vision loss in a patient with granulomatosis with polyangiitis |
title | Atypical painless vision loss in a patient with granulomatosis with polyangiitis |
title_full | Atypical painless vision loss in a patient with granulomatosis with polyangiitis |
title_fullStr | Atypical painless vision loss in a patient with granulomatosis with polyangiitis |
title_full_unstemmed | Atypical painless vision loss in a patient with granulomatosis with polyangiitis |
title_short | Atypical painless vision loss in a patient with granulomatosis with polyangiitis |
title_sort | atypical painless vision loss in a patient with granulomatosis with polyangiitis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745643/ https://www.ncbi.nlm.nih.gov/pubmed/33384913 http://dx.doi.org/10.3205/oc000173 |
work_keys_str_mv | AT nelsonpatriciac atypicalpainlessvisionlossinapatientwithgranulomatosiswithpolyangiitis AT kunamvamsi atypicalpainlessvisionlossinapatientwithgranulomatosiswithpolyangiitis AT prosperoponceclaudia atypicalpainlessvisionlossinapatientwithgranulomatosiswithpolyangiitis |