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Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center

Introduction  Repeat transurethral resection of bladder tumor (ReTURBT) has become an integral part of the management of superficial bladder cancers at various urological centers around the world. Early detection of residual disease, leading to upstaging in some cases, leads to decrease in recurrenc...

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Autores principales: Raja, Anand, Malik, Kanuj, Arunandhichelvan, Arulmolichelvan, Kathiresan, N., Ravishankar, L. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745745/
https://www.ncbi.nlm.nih.gov/pubmed/33354550
http://dx.doi.org/10.1055/s-0040-1721213
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author Raja, Anand
Malik, Kanuj
Arunandhichelvan, Arulmolichelvan
Kathiresan, N.
Ravishankar, L. S.
author_facet Raja, Anand
Malik, Kanuj
Arunandhichelvan, Arulmolichelvan
Kathiresan, N.
Ravishankar, L. S.
author_sort Raja, Anand
collection PubMed
description Introduction  Repeat transurethral resection of bladder tumor (ReTURBT) has become an integral part of the management of superficial bladder cancers at various urological centers around the world. Early detection of residual disease, leading to upstaging in some cases, leads to decrease in recurrence rates. Our study aimed to analyze the impact of ReTURBT in detecting residual tumor and tumor recurrences, hence validating the benefits of procedure as a routine. Materials and Methods  A total of 152 patients with superficial bladder cancer who were treated at Cancer Institute (WIA) between January 2005 and December 2013 were analyzed and followed up for 3 years. Results  Of the 152 cases who underwent ReTURBT, 47 patients had residue in the final histopathology of the resected specimen (31%). The overall rate of upstaging to muscle-invasive disease following ReTURBT was 3.3%. The mean follow-up period was 47.13 months, during which 25 (17%) out of 147 patients who underwent ReTURBT had disease recurrence. There was no additional morbidity due to ReTURBT as compared with the primary procedure. Conclusion  ReTURBT is an effective procedure in treating recurrent tumors also as long as they remain superficial. The procedure when performed with utmost care in experienced hands remains a very safe procedure to be followed as a routine and standard.
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spelling pubmed-77457452020-12-21 Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center Raja, Anand Malik, Kanuj Arunandhichelvan, Arulmolichelvan Kathiresan, N. Ravishankar, L. S. South Asian J Cancer Introduction  Repeat transurethral resection of bladder tumor (ReTURBT) has become an integral part of the management of superficial bladder cancers at various urological centers around the world. Early detection of residual disease, leading to upstaging in some cases, leads to decrease in recurrence rates. Our study aimed to analyze the impact of ReTURBT in detecting residual tumor and tumor recurrences, hence validating the benefits of procedure as a routine. Materials and Methods  A total of 152 patients with superficial bladder cancer who were treated at Cancer Institute (WIA) between January 2005 and December 2013 were analyzed and followed up for 3 years. Results  Of the 152 cases who underwent ReTURBT, 47 patients had residue in the final histopathology of the resected specimen (31%). The overall rate of upstaging to muscle-invasive disease following ReTURBT was 3.3%. The mean follow-up period was 47.13 months, during which 25 (17%) out of 147 patients who underwent ReTURBT had disease recurrence. There was no additional morbidity due to ReTURBT as compared with the primary procedure. Conclusion  ReTURBT is an effective procedure in treating recurrent tumors also as long as they remain superficial. The procedure when performed with utmost care in experienced hands remains a very safe procedure to be followed as a routine and standard. Thieme Medical and Scientific Publishers Pvt. Ltd 2020-06 2020-12-14 /pmc/articles/PMC7745745/ /pubmed/33354550 http://dx.doi.org/10.1055/s-0040-1721213 Text en MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Raja, Anand
Malik, Kanuj
Arunandhichelvan, Arulmolichelvan
Kathiresan, N.
Ravishankar, L. S.
Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center
title Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center
title_full Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center
title_fullStr Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center
title_full_unstemmed Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center
title_short Utility and Safety of Repeat Transurethral Resection of Bladder Tumor Performed at a Tertiary Center
title_sort utility and safety of repeat transurethral resection of bladder tumor performed at a tertiary center
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745745/
https://www.ncbi.nlm.nih.gov/pubmed/33354550
http://dx.doi.org/10.1055/s-0040-1721213
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