Seipin regulates the formation of nuclear lipid droplets from a distance

Nuclear lipid droplets (nLDs) are poorly characterized outside of the liver. In this issue, Sołtysik et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202005026) show that seipin is absent from the nucleus but seipin deficiency promotes nLD formation by increasing nuclear phosphatidic acid.

Detalles Bibliográficos
Autores principales: Du, Ximing, Yang, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745754/
https://www.ncbi.nlm.nih.gov/pubmed/33320190
http://dx.doi.org/10.1083/jcb.202011166
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author Du, Ximing
Yang, Hongyuan
author_facet Du, Ximing
Yang, Hongyuan
author_sort Du, Ximing
collection PubMed
description Nuclear lipid droplets (nLDs) are poorly characterized outside of the liver. In this issue, Sołtysik et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202005026) show that seipin is absent from the nucleus but seipin deficiency promotes nLD formation by increasing nuclear phosphatidic acid.
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spelling pubmed-77457542021-07-04 Seipin regulates the formation of nuclear lipid droplets from a distance Du, Ximing Yang, Hongyuan J Cell Biol Spotlight Nuclear lipid droplets (nLDs) are poorly characterized outside of the liver. In this issue, Sołtysik et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202005026) show that seipin is absent from the nucleus but seipin deficiency promotes nLD formation by increasing nuclear phosphatidic acid. Rockefeller University Press 2020-12-15 /pmc/articles/PMC7745754/ /pubmed/33320190 http://dx.doi.org/10.1083/jcb.202011166 Text en © 2020 Du and Yang http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Du, Ximing
Yang, Hongyuan
Seipin regulates the formation of nuclear lipid droplets from a distance
title Seipin regulates the formation of nuclear lipid droplets from a distance
title_full Seipin regulates the formation of nuclear lipid droplets from a distance
title_fullStr Seipin regulates the formation of nuclear lipid droplets from a distance
title_full_unstemmed Seipin regulates the formation of nuclear lipid droplets from a distance
title_short Seipin regulates the formation of nuclear lipid droplets from a distance
title_sort seipin regulates the formation of nuclear lipid droplets from a distance
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745754/
https://www.ncbi.nlm.nih.gov/pubmed/33320190
http://dx.doi.org/10.1083/jcb.202011166
work_keys_str_mv AT duximing seipinregulatestheformationofnuclearlipiddropletsfromadistance
AT yanghongyuan seipinregulatestheformationofnuclearlipiddropletsfromadistance

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