Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies

Illumina DNA methylation arrays are a widely used tool for performing genome-wide DNA methylation analyses. However, measurements obtained from these arrays may be affected by technical artefacts that result in spurious associations if left unchecked. Cross-reactivity represents one of the major cha...

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Detalles Bibliográficos
Autores principales: Hop, Paul J, Zwamborn, Ramona A J, Hannon, Eilis J, Dekker, Annelot M, van Eijk, Kristel R, Walker, Emma M, Iacoangeli, Alfredo, Jones, Ashley R, Shatunov, Aleksey, Khleifat, Ahmad Al, Opie-Martin, Sarah, Shaw, Christopher E, Morrison, Karen E, Shaw, Pamela J, McLaughlin, Russell L, Hardiman, Orla, Al-Chalabi, Ammar, Van Den Berg, Leonard H, Mill, Jonathan, Veldink, Jan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745769/
https://www.ncbi.nlm.nih.gov/pubmed/33554115
http://dx.doi.org/10.1093/nargab/lqaa105

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