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Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system

BACKGROUND: New York City (NYC) bore the greatest burden of COVID-19 in the United States early in the pandemic. In this case series, we describe characteristics and outcomes of racially and ethnically diverse patients tested for and hospitalized with COVID-19 in New York City’s public hospital syst...

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Autores principales: Kalyanaraman Marcello, Roopa, Dolle, Johanna, Grami, Sheila, Adule, Richard, Li, Zeyu, Tatem, Kathleen, Anyaogu, Chinyere, Apfelroth, Stephen, Ayinla, Raji, Boma, Noella, Brady, Terence, Cosme-Thormann, Braulio F., Costarella, Roseann, Ford, Kenra, Gaither, Kecia, Jacobson, Jessica, Kanter, Marc, Kessler, Stuart, Kristal, Ross B., Lieber, Joseph J., Mukherjee, Vikramjit, Rizzo, Vincent, Rowell, Madden, Stevens, David, Sydney, Elana, Wallach, Andrew, Chokshi, Dave A., Davis, Nichola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745980/
https://www.ncbi.nlm.nih.gov/pubmed/33332356
http://dx.doi.org/10.1371/journal.pone.0243027
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author Kalyanaraman Marcello, Roopa
Dolle, Johanna
Grami, Sheila
Adule, Richard
Li, Zeyu
Tatem, Kathleen
Anyaogu, Chinyere
Apfelroth, Stephen
Ayinla, Raji
Boma, Noella
Brady, Terence
Cosme-Thormann, Braulio F.
Costarella, Roseann
Ford, Kenra
Gaither, Kecia
Jacobson, Jessica
Kanter, Marc
Kessler, Stuart
Kristal, Ross B.
Lieber, Joseph J.
Mukherjee, Vikramjit
Rizzo, Vincent
Rowell, Madden
Stevens, David
Sydney, Elana
Wallach, Andrew
Chokshi, Dave A.
Davis, Nichola
author_facet Kalyanaraman Marcello, Roopa
Dolle, Johanna
Grami, Sheila
Adule, Richard
Li, Zeyu
Tatem, Kathleen
Anyaogu, Chinyere
Apfelroth, Stephen
Ayinla, Raji
Boma, Noella
Brady, Terence
Cosme-Thormann, Braulio F.
Costarella, Roseann
Ford, Kenra
Gaither, Kecia
Jacobson, Jessica
Kanter, Marc
Kessler, Stuart
Kristal, Ross B.
Lieber, Joseph J.
Mukherjee, Vikramjit
Rizzo, Vincent
Rowell, Madden
Stevens, David
Sydney, Elana
Wallach, Andrew
Chokshi, Dave A.
Davis, Nichola
author_sort Kalyanaraman Marcello, Roopa
collection PubMed
description BACKGROUND: New York City (NYC) bore the greatest burden of COVID-19 in the United States early in the pandemic. In this case series, we describe characteristics and outcomes of racially and ethnically diverse patients tested for and hospitalized with COVID-19 in New York City’s public hospital system. METHODS: We reviewed the electronic health records of all patients who received a SARS-CoV-2 test between March 5 and April 9, 2020, with follow up through April 16, 2020. The primary outcomes were a positive test, hospitalization, and death. Demographics and comorbidities were also assessed. RESULTS: 22254 patients were tested for SARS-CoV-2. 13442 (61%) were positive; among those, the median age was 52.7 years (interquartile range [IQR] 39.5–64.5), 7481 (56%) were male, 3518 (26%) were Black, and 4593 (34%) were Hispanic. Nearly half (4669, 46%) had at least one chronic disease (27% diabetes, 30% hypertension, and 21% cardiovascular disease). Of those testing positive, 6248 (46%) were hospitalized. The median age was 61.6 years (IQR 49.7–72.9); 3851 (62%) were male, 1950 (31%) were Black, and 2102 (34%) were Hispanic. More than half (3269, 53%) had at least one chronic disease (33% diabetes, 37% hypertension, 24% cardiovascular disease, 11% chronic kidney disease). 1724 (28%) hospitalized patients died. The median age was 71.0 years (IQR 60.0, 80.9); 1087 (63%) were male, 506 (29%) were Black, and 528 (31%) were Hispanic. Chronic diseases were common (35% diabetes, 37% hypertension, 28% cardiovascular disease, 15% chronic kidney disease). Male sex, older age, diabetes, cardiac history, and chronic kidney disease were significantly associated with testing positive, hospitalization, and death. Racial/ethnic disparities were observed across all outcomes. CONCLUSIONS AND RELEVANCE: This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in New York City to date. Our findings highlight disparities in outcomes that can inform prevention and testing recommendations.
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spelling pubmed-77459802020-12-31 Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system Kalyanaraman Marcello, Roopa Dolle, Johanna Grami, Sheila Adule, Richard Li, Zeyu Tatem, Kathleen Anyaogu, Chinyere Apfelroth, Stephen Ayinla, Raji Boma, Noella Brady, Terence Cosme-Thormann, Braulio F. Costarella, Roseann Ford, Kenra Gaither, Kecia Jacobson, Jessica Kanter, Marc Kessler, Stuart Kristal, Ross B. Lieber, Joseph J. Mukherjee, Vikramjit Rizzo, Vincent Rowell, Madden Stevens, David Sydney, Elana Wallach, Andrew Chokshi, Dave A. Davis, Nichola PLoS One Research Article BACKGROUND: New York City (NYC) bore the greatest burden of COVID-19 in the United States early in the pandemic. In this case series, we describe characteristics and outcomes of racially and ethnically diverse patients tested for and hospitalized with COVID-19 in New York City’s public hospital system. METHODS: We reviewed the electronic health records of all patients who received a SARS-CoV-2 test between March 5 and April 9, 2020, with follow up through April 16, 2020. The primary outcomes were a positive test, hospitalization, and death. Demographics and comorbidities were also assessed. RESULTS: 22254 patients were tested for SARS-CoV-2. 13442 (61%) were positive; among those, the median age was 52.7 years (interquartile range [IQR] 39.5–64.5), 7481 (56%) were male, 3518 (26%) were Black, and 4593 (34%) were Hispanic. Nearly half (4669, 46%) had at least one chronic disease (27% diabetes, 30% hypertension, and 21% cardiovascular disease). Of those testing positive, 6248 (46%) were hospitalized. The median age was 61.6 years (IQR 49.7–72.9); 3851 (62%) were male, 1950 (31%) were Black, and 2102 (34%) were Hispanic. More than half (3269, 53%) had at least one chronic disease (33% diabetes, 37% hypertension, 24% cardiovascular disease, 11% chronic kidney disease). 1724 (28%) hospitalized patients died. The median age was 71.0 years (IQR 60.0, 80.9); 1087 (63%) were male, 506 (29%) were Black, and 528 (31%) were Hispanic. Chronic diseases were common (35% diabetes, 37% hypertension, 28% cardiovascular disease, 15% chronic kidney disease). Male sex, older age, diabetes, cardiac history, and chronic kidney disease were significantly associated with testing positive, hospitalization, and death. Racial/ethnic disparities were observed across all outcomes. CONCLUSIONS AND RELEVANCE: This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in New York City to date. Our findings highlight disparities in outcomes that can inform prevention and testing recommendations. Public Library of Science 2020-12-17 /pmc/articles/PMC7745980/ /pubmed/33332356 http://dx.doi.org/10.1371/journal.pone.0243027 Text en © 2020 Kalyanaraman Marcello et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kalyanaraman Marcello, Roopa
Dolle, Johanna
Grami, Sheila
Adule, Richard
Li, Zeyu
Tatem, Kathleen
Anyaogu, Chinyere
Apfelroth, Stephen
Ayinla, Raji
Boma, Noella
Brady, Terence
Cosme-Thormann, Braulio F.
Costarella, Roseann
Ford, Kenra
Gaither, Kecia
Jacobson, Jessica
Kanter, Marc
Kessler, Stuart
Kristal, Ross B.
Lieber, Joseph J.
Mukherjee, Vikramjit
Rizzo, Vincent
Rowell, Madden
Stevens, David
Sydney, Elana
Wallach, Andrew
Chokshi, Dave A.
Davis, Nichola
Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system
title Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system
title_full Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system
title_fullStr Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system
title_full_unstemmed Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system
title_short Characteristics and outcomes of COVID-19 patients in New York City’s public hospital system
title_sort characteristics and outcomes of covid-19 patients in new york city’s public hospital system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745980/
https://www.ncbi.nlm.nih.gov/pubmed/33332356
http://dx.doi.org/10.1371/journal.pone.0243027
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