A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course

Hepatocellular carcinoma is one of the most common liver malignancies in the United States. Poor prognosis is associated with paraneoplastic syndromes such as hypercalcemia, hypercholesterolemia, or hypoglycemia. Hypercalcemia as a paraneoplastic syndrome of hepatocellular carcinoma has been rarely...

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Autores principales: Castro-Camero, Pamela, Park, Bumsoo, Gupta, Amit, Vemulapalli, Raghavendra, Shreve, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MSU College of Osteopathic Medicine Statewide Campus System 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746133/
https://www.ncbi.nlm.nih.gov/pubmed/33655160
http://dx.doi.org/10.51894/001c.8983
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author Castro-Camero, Pamela
Park, Bumsoo
Gupta, Amit
Vemulapalli, Raghavendra
Shreve, Maria
author_facet Castro-Camero, Pamela
Park, Bumsoo
Gupta, Amit
Vemulapalli, Raghavendra
Shreve, Maria
author_sort Castro-Camero, Pamela
collection PubMed
description Hepatocellular carcinoma is one of the most common liver malignancies in the United States. Poor prognosis is associated with paraneoplastic syndromes such as hypercalcemia, hypercholesterolemia, or hypoglycemia. Hypercalcemia as a paraneoplastic syndrome of hepatocellular carcinoma has been rarely reported. We report a mortality case of incidentally diagnosed hepatocellular carcinoma associated with humoral hypercalcemia of malignancy. The patient demonstrated a fulminant disease course with an unexpected fatal outcome within 40 days of initial diagnosis. Our case can suggest importance of early definitive treatment of hepatocellular carcinoma, extremely close monitoring, and aggressive medical treatment when it is associated with humoral hypercalcemia of malignancy.
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spelling pubmed-77461332021-03-01 A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course Castro-Camero, Pamela Park, Bumsoo Gupta, Amit Vemulapalli, Raghavendra Shreve, Maria Spartan Med Res J Case Report Hepatocellular carcinoma is one of the most common liver malignancies in the United States. Poor prognosis is associated with paraneoplastic syndromes such as hypercalcemia, hypercholesterolemia, or hypoglycemia. Hypercalcemia as a paraneoplastic syndrome of hepatocellular carcinoma has been rarely reported. We report a mortality case of incidentally diagnosed hepatocellular carcinoma associated with humoral hypercalcemia of malignancy. The patient demonstrated a fulminant disease course with an unexpected fatal outcome within 40 days of initial diagnosis. Our case can suggest importance of early definitive treatment of hepatocellular carcinoma, extremely close monitoring, and aggressive medical treatment when it is associated with humoral hypercalcemia of malignancy. MSU College of Osteopathic Medicine Statewide Campus System 2019-07-01 /pmc/articles/PMC7746133/ /pubmed/33655160 http://dx.doi.org/10.51894/001c.8983 Text en https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (4.0) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Castro-Camero, Pamela
Park, Bumsoo
Gupta, Amit
Vemulapalli, Raghavendra
Shreve, Maria
A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course
title A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course
title_full A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course
title_fullStr A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course
title_full_unstemmed A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course
title_short A Case of Humoral Hypercalcemia of Malignancy Secondary to Hepatocellular Carcinoma with Fulminant Clinical Course
title_sort case of humoral hypercalcemia of malignancy secondary to hepatocellular carcinoma with fulminant clinical course
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746133/
https://www.ncbi.nlm.nih.gov/pubmed/33655160
http://dx.doi.org/10.51894/001c.8983
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