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Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion

OBJECTIVES: Residual cysts are relatively rare inflammatory cysts of the jaws. They are essentially radicular cysts without the presence of the offending dentition. These lesions have the ability to destroy bone within the jaws without any symptoms. Moreover, they can mimic more aggressive cysts and...

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Autores principales: Titinchi, Fadi, Morkel, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746164/
https://www.ncbi.nlm.nih.gov/pubmed/33332452
http://dx.doi.org/10.1371/journal.pone.0244250
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author Titinchi, Fadi
Morkel, Jean
author_facet Titinchi, Fadi
Morkel, Jean
author_sort Titinchi, Fadi
collection PubMed
description OBJECTIVES: Residual cysts are relatively rare inflammatory cysts of the jaws. They are essentially radicular cysts without the presence of the offending dentition. These lesions have the ability to destroy bone within the jaws without any symptoms. Moreover, they can mimic more aggressive cysts and tumours on radiographs. The aim of this study was to describe the clinico-pathological features of residual cysts in order to discern them from other cystic lesions as well as analyse their management and recurrence patterns. MATERIALS AND METHODS: Sixty-four histopathologically confirmed residual cysts were analysed based on their clinical, radiological and histopathological features. Their management and follow-up were also noted. RESULTS: The majority of lesions presented in elderly (46.8%), edentulous patients (60.9%) and were most commonly found in the posterior regions of the mandible (51.6%). Clinico-pathological features that aided in their diagnosis included long-standing history with slow growing swelling and presence of well-defined, unilocular cystic lesion associated with previously extracted dentition. Enucleation was a successful method in the management of residual cysts with very low recurrence rate (1.6%). Two patients (3.1%) developed squamous cell carcinoma from the cyst lining. CONCLUSION: Residual cysts should be high on the list of differential diagnosis when elderly, edentulous patients present with cystic lesions in the jaws compared to dentate patients (P<0.01). All lesions should by biopsied and sent for histopathological examination along with radiological correlation as they have the potential to transform into primary intra-osseous squamous cell carcinoma with devastating consequences to the patient.
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spelling pubmed-77461642020-12-31 Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion Titinchi, Fadi Morkel, Jean PLoS One Research Article OBJECTIVES: Residual cysts are relatively rare inflammatory cysts of the jaws. They are essentially radicular cysts without the presence of the offending dentition. These lesions have the ability to destroy bone within the jaws without any symptoms. Moreover, they can mimic more aggressive cysts and tumours on radiographs. The aim of this study was to describe the clinico-pathological features of residual cysts in order to discern them from other cystic lesions as well as analyse their management and recurrence patterns. MATERIALS AND METHODS: Sixty-four histopathologically confirmed residual cysts were analysed based on their clinical, radiological and histopathological features. Their management and follow-up were also noted. RESULTS: The majority of lesions presented in elderly (46.8%), edentulous patients (60.9%) and were most commonly found in the posterior regions of the mandible (51.6%). Clinico-pathological features that aided in their diagnosis included long-standing history with slow growing swelling and presence of well-defined, unilocular cystic lesion associated with previously extracted dentition. Enucleation was a successful method in the management of residual cysts with very low recurrence rate (1.6%). Two patients (3.1%) developed squamous cell carcinoma from the cyst lining. CONCLUSION: Residual cysts should be high on the list of differential diagnosis when elderly, edentulous patients present with cystic lesions in the jaws compared to dentate patients (P<0.01). All lesions should by biopsied and sent for histopathological examination along with radiological correlation as they have the potential to transform into primary intra-osseous squamous cell carcinoma with devastating consequences to the patient. Public Library of Science 2020-12-17 /pmc/articles/PMC7746164/ /pubmed/33332452 http://dx.doi.org/10.1371/journal.pone.0244250 Text en © 2020 Titinchi, Morkel http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Titinchi, Fadi
Morkel, Jean
Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion
title Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion
title_full Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion
title_fullStr Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion
title_full_unstemmed Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion
title_short Residual cyst of the jaws: A clinico-pathologic study of this seemingly inconspicuous lesion
title_sort residual cyst of the jaws: a clinico-pathologic study of this seemingly inconspicuous lesion
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746164/
https://www.ncbi.nlm.nih.gov/pubmed/33332452
http://dx.doi.org/10.1371/journal.pone.0244250
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