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SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells

Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2 infection, although the mechanism for initiation of a hyper-inflammatory response, and multi-organ damage from viral infection is poorly understood. In this virus-cell interaction study, we observed that SARS-...

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Detalles Bibliográficos
Autores principales:	Patra, Tapas, Meyer, Keith, Geerling, Lizzie, Isbell, T. Scott, Hoft, Daniel F., Brien, James, Pinto, Amelia K., Ray, Ratna B., Ray, Ranjit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746263/ https://www.ncbi.nlm.nih.gov/pubmed/33284859 http://dx.doi.org/10.1371/journal.ppat.1009128

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