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Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly
Bunyavirus ribonucleoprotein (RNP) that is assembled by polymerized nucleoproteins (N) coating a viral RNA and associating with a viral polymerase can be both the RNA synthesis machinery and the structural core of virions. Bunyaviral N and RNP thus could be assailable targets for host antiviral defe...
Autores principales: | Mo, Qiong, Xu, Zhao, Deng, Fei, Wang, Hualin, Ning, Yun-Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746268/ https://www.ncbi.nlm.nih.gov/pubmed/33284835 http://dx.doi.org/10.1371/journal.ppat.1009129 |
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