USP10 deletion inhibits macrophage-derived foam cell formation and cellular-oxidized low density lipoprotein uptake by promoting the degradation of CD36

Foam cell formation process is involved in the pathogenesis of atherosclerosis (AS). Activation of this biological process depends on lipid uptake by scavenger receptors, such as CD36, SR-A and SR-B1. Among these receptors, CD36 is the principal one because it dominates roughly 50% lipid uptake in m...

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Detalles Bibliográficos
Autores principales: Xia, Xiaohong, Hu, Tumei, He, Jinchan, Xu, Qiong, Yu, Cuifu, Liu, Xiaolin, Shao, Zhenlong, Liao, Yuning, Huang, Hongbiao, Liu, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746336/
https://www.ncbi.nlm.nih.gov/pubmed/33197885
http://dx.doi.org/10.18632/aging.104003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746336/
https://www.ncbi.nlm.nih.gov/pubmed/33197885
http://dx.doi.org/10.18632/aging.104003

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