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Silencing KIF14 reverses acquired resistance to sorafenib in hepatocellular carcinoma
For nearly a decade, sorafenib has served as a first-line chemotherapeutic drug for the treatment of hepatocellular carcinoma (HCC), but it displays only limited efficacy against advanced drug-resistant HCC. Regorafenib, the first second-line drug approved for treatment after sorafenib failure, can...
Autores principales: | Zhu, Qiankun, Ren, Haiyang, Li, Xiaodong, Qian, Bo, Fan, Shengjie, Hu, Fengli, Xu, Lishan, Zhai, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746348/ https://www.ncbi.nlm.nih.gov/pubmed/33203790 http://dx.doi.org/10.18632/aging.104028 |
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