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Inflammatory factors and amyloid β-induced microglial polarization promote inflammatory crosstalk with astrocytes

The immunological responses are a key pathological factor in Alzheimer’s disease (AD). We hypothesized that microglial polarization alters microglia-astrocyte immune interactions in AD. M1 and M2 microglia were isolated from primary rat microglia and were confirmed to secrete pro-inflammatory and an...

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Detalles Bibliográficos
Autores principales: Xie, Lushuang, Zhang, Ning, Zhang, Qun, Li, Chenyu, Sandhu, Aaron F., III, George Williams, Lin, Sirui, Lv, PeiRan, Liu, Yi, Wu, Qiaofeng, Yu, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746366/
https://www.ncbi.nlm.nih.gov/pubmed/33196457
http://dx.doi.org/10.18632/aging.103663