Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization

Necrotizing enterocolitis (NEC) is a life-threatening inflammatory disease in newborns, but the mechanisms remain unclear. Interferon regulatory factor 5 (IRF5) is a master regulator of macrophage function and is essential for proinflammatory M1 macrophage polarization. Our previous data indicated t...

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Detalles Bibliográficos
Autores principales: Wei, Jia, Tang, Daxing, Lu, Chengjie, Yang, Jin, Lu, Yulei, Wang, Yidong, Jia, Liangliang, Wang, Jianfang, Ru, Wei, Lu, Yi, Cai, Zhejun, Shu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746522/
https://www.ncbi.nlm.nih.gov/pubmed/31086271
http://dx.doi.org/10.1038/s41385-019-0169-x

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