Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL cell interactions with the supportive tissue microenvironment play a critical...

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Detalles Bibliográficos
Autores principales: Gimenez, Neus, Tripathi, Rupal, Giró, Ariadna, Rosich, Laia, López-Guerra, Mònica, López-Oreja, Irene, Playa-Albinyana, Heribert, Arenas, Fabian, Mas, José Manuel, Pérez-Galán, Patricia, Delgado, Julio, Campo, Elias, Farrés, Judith, Colomer, Dolors
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746765/
https://www.ncbi.nlm.nih.gov/pubmed/33335123
http://dx.doi.org/10.1038/s41598-020-78315-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746765/
https://www.ncbi.nlm.nih.gov/pubmed/33335123
http://dx.doi.org/10.1038/s41598-020-78315-0

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